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2022, Number 1-2

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Rev Cent Dermatol Pascua 2022; 31 (1-2)

Multinucleate cell angiohistiocytoma

Navarrete-Franco G, González-González M, Ramos-Garibay JA, Laguna-Meraz JP

Language: Spanish
References: 16
Page: 26-29
PDF size: 362.75 Kb.


ABSTRACT

Multinucleate cell angiohistiocytoma (MCAH) is a vascular and fibrohistiocytic proliferation of still uncertain origin. First described by Smith and Wilson-Jones in 1985; it is a rare dermatosis, the classic form mainly affects middle-aged women and usually presents unilaterally, frequently affecting acral regions and the face. Morphologically, they are numerous, dome-shaped neoformations with a smooth surface; erythematous, erythematous-violaceous and/or brown, isolated and/or confluent forming plaques of variable size and shape. Disseminated cases with different epidemiological and morphological characteristics have been described. Diagnosis is based on histopathological findings, which include vascular capillary proliferation in the superficial dermis with the presence of multinucleated cells immersed in a fibrous stroma. The picture evolves slowly and tend to be persistent; although there are cases of spontaneous involution. The treatment of choice is surgical removal, when possible, and surveillance is an alternative given the benign nature of this entity.


REFERENCES

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