2022, Number 10
<< Back
Ginecol Obstet Mex 2022; 90 (10)
Necrotic type of Lipschütz ulcer
Benito-Vielba M, Pellicer A, Baquedano-Mainar L, Lapresta-Moros M, Colmenarejo F
Language: Spanish
References: 15
Page: 864-868
PDF size: 200.02 Kb.
ABSTRACT
Introduction: Lipschütz ulcers are an infrequent cause of genital ulcer, of spontaneous
relief and almost always benign, although in some patients they may leave
genital scars. They usually appear in young women, before the onset of active sexual
life, coinciding with a catarrhal or flu-like condition.
Clinical case: 18-year-old female patient with a painful vulvar ulcer, coinciding
with an episode of acute tonsillitis and fever of 38 ºC. The patient denied having had
sexual intercourse. The ulcer was 3 to 4 cm, deep, purulent, with opening of the right
labium minora and with a significant necrotic component. For pain control she was
prescribed corticosteroids, oral doxycycline, lidocaine cream and anti-inflammatory
drugs. Laboratory tests ruled out sexually transmitted infection. At the end of the
prescribed therapeutic scheme the evolution was favorable, with disappearance of
symptoms, but with a sequel: opening of the right labium majus.
Conclusions: Lipschütz ulcer is a rare cause of vulvar ulcer. Its treatment consists
of symptom control and it almost always heals within 4 to 6 weeks, leaving no lesions.
The diagnosis can only be established after other more frequent causes of vulvar ulceration
have been excluded.
REFERENCES
Mourinha V, Costa S, Urzal C, Guerreiro F. Lipschütz ulcers:uncommon diagnosis of vulvar ulcerations. BMJ Case Rep 2016; 2016. http://dx.doi.org/10.1136/bcr-2015-214338
Vismara SA, Lava SAG, Kottanattu L, et al. Lipschütz’s acutevulvar ulcer: a systematic review. Eur J Pediatr 2020;179:1559. https://doi.org/10.1007/s00431-020-03647-y
Pereira DAG, Teixeira EPP, Lopes ACM, Sarmento RJP, LopesAPC. Lipschütz Ulcer: An Unusual Diagnosis that ShouldNot be Neglected. Rev Bras Ginecol Obstet. 2021; 43 (5):
414-16. doi: 10.1055/s-0041-17291474. Di Lernia V, Mansouri Y. Epstein-Barr virus and skin manifestationsin childhood. Int J Dermatol 2013; 52:1177. https://doi.org/10.1111/j.1365-4632.2012.05855.x
Schindler Leal AA, Piccinato CA, Beck APA, Gomes MTV,Podgaec S. Acute genital ulcers: keep Lipschütz ulcer inmind. Arch Gynecol Obstet 2018; 298 (5): 927-31. https://doi.org/10.1007/s00404-018-4866-6
Lipschütz B. Über eune eugenartige Geschwürsform desweiblichen Genitales (Ulcus vulvae acutum). Arch DermatolSyph 1913;114:363-95.
Halvorse JA, Brevig T, Aas T, et al. Genital ulcers as initialmanifestation of Epstein-Barr virus infection: two newcases and a review of the literatura. Acta Derm Venereol2006; 86: 439.
Popatia S, Chiu YE. Vulvar aphthous ulcer after COVID-19vaccination. Pediatr Dermatol 2022; 39 (1): 153-154. doi:10.1111/pde.14881
Wojcicki AV, O'Flynn O'Brien KL. Vulvar Aphthous Ulcer inan Adolescent After Pfizer-BioNTech (BNT162b2) COVID-19Vaccination. J Pediatr Adolesc Gynecol. 2021 :S1083-3188(21) 00304-1. doi: 10.1016/j.jpag.2021.10.005
Arellano J, Fuentes E, Moreno P, Corredoira Y. Úlcera deLipschütz, un diagnóstico para considerar en la poblaciónpediátrica [Ulcer of Lipschütz, a diagnosis to consider inthe pediatric population]. Arch Argent Pediatr 2019; 117(3): e305-e308. http://dx.doi.org/10.5546/aap.2019.e305
Morgado-Carrasco D, Bosch-Amate X, Fustà-Novell X, GiavedoniP. Lipschütz ulcer: an acute noninfectious genital ulcerto bear in mind in adult women. Actas Dermosifiliogr (EnglEd). 2020 Sep; 111 (7): 624-26. doi: 10.1016/j.ad.2018.12.011
Plácido Paias R, Portillo Márquez M, Del Castillo Navio E,González Carracedo MJ, Vaquerizo Vaquerizo U. Úlcerade Lipschütz en su forma gangrenosa. Rev Pediatr AtenPrimaria 2014; 16: e151-4. https://dx.doi.org/10.4321/S1139-76322014000500013
Vieira-Baptista P, Lima-Silva J, Beires j, Martínez de OliveiraJ. Lipschütz ulcers: should we rethink this? An analysis of33 cases. Eur J Obstet Gynecol Reprod Biol 2016; 198:149.https://doi.org/10.1016/j.ejogrb.2015.07.016
Huppert JS. Lipschutz ulcers: evaluation and managementof acute genital ulcers in women. Dermatol Ther 2010; 23:533. https://doi.org/10.1111/j.1529-8019.2010.01356.x
Rosman IS, Berk DR, Bayliss SJ, et al. Acute genital ulcersin nonsexually active young girls: case series, review ofthe literatura, and evaluation and management recommendations.Pediatr Dermatol 2012; 29: 147. https://doi.org/10.1111/j.15251470.2011.01589.x