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2021, Number 2

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Rev Cub de Med Fis y Rehab 2021; 13 (2)

Safety of ozone therapy applied by different routes in patients with ischemic stroke

Cordero EA, Peña SM, González GS, Borroto RV, Padilla PE

Language: Spanish
References: 28
Page: 1-18
PDF size: 579.49 Kb.


ABSTRACT

Introduction: Cerebrovascular disease is the leading cause of disability in adults worldwide. Stroke is the most common variant of this type of condition. Ozone therapy has been proposed as an effective treatment for stroke and it is even recommended for prevention.
Objective: To describe the frequency and safety of ozone application by different routes and combinations during the rehabilitation of patients with ischaemic ischemic stroke.
Methods: A retrospective descriptive study was carried out in 247 patients of both sexes who suffered ischemic stroke and received ozone therapy for rehabilitation. The different application routes evaluated for medical ozone, weather single or combined, were major autohemotherapy, rectal insufflation, intra-articular infiltration, as well as infiltration at trigger points and acupuncture points. Adverse reactions were collected.
Results: The total number of ozone applications was 7410. Rectal insufflation was the most used route (52.9%). Microdosing with ozone in trigger points and acupuncture was the most frequently applied therapy (96.4%). Autohemotherapy predominated in younger patients (98.6%). Rectal insufflation and ozonopuncture were the most frequent combined therapies (72.1%). There were only six adverse events (2.43%): four mild (1.62%) and two moderate (0.81%). In these cases it was not necessary to interrupt treatment during recovery.
Conclusions: The ozone application routes and the combinations used in the treatment of patients with ischemic stroke during their rehabilitation were found to be safe from a pharmacological point of view.


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