Cepeda-Uceta MM, Moya-Martínez R, Zerpa-Zerpa V, Tresserra-Casas F, Doménech-Juan I

Language: Spanish
References: 17
Page: 228-234
PDF size: 226.62 Kb.

ABSTRACT

Background: Chondrosarcomas make up a group of tumors with a wide spectrum of clinical and pathological findings, which have as a common characteristic the production of neoplastic cartilage of unknown cause, they constitute 10% of malignant bone tumors, of these between 2% and 5% are located in the head and neck region. In laryngeal lesions, the most frequent is at the level of the cricoid, the main clinical sign is dysphonia and/or dyspnea. Complementary imaging studies do not allow the distinction between chondromas and chondrosarcomas, requiring a histological diagnosis of certainty through a biopsy.
Clinical case: A 68-year-old female patient with dyspnea on exertion, who after surgical treatment was diagnosed by histopathological examination as a clear cell cricoid chondrosarcoma and later presented an intercostal metastasis; tumor that has been highlighted due to its low frequency in the head and neck area.
Conclusions: The classic treatment of chondrosarcomas of the larynx is radical surgery with negative margins, with an excellent prognosis if adequate resection is performed.

REFERENCES

1. Robbins y Cotran. Patología estructural y funcional. 7ª ed.España: Elsevier, 2010; 13023.

2. Pacheco OL, Pontón VP, Borja HT, Ayala OA . Condrosarcomade la laringe. Reporte de un caso y revisión de laliteratura. Rev Otorrinolaringol Cir Cabeza Cuello 2017; 77(2): 175-180. doi.org/10.4067/S0718-48162017000200009

3. Thompson LDR, Gannon FH. Chondrosarcoma of the larynx:a clinicopathologic study of 111 cases with a review ofthe literature. Am J Surg Pathol 2002; 26 (7): 836-51. doi:10.1097/00000478-200207000-00002.

4. Rojas R. Condrosarcoma laríngeo. An Radiol Méx 2004;1: 29-32.

5. Cadena-Piñeros E, Romero-Rojas AE, Vargas SE. Condrosarcomalaríngeo: una patología poco usual. Rev Fac Med2011;59 (2): 155-161.

6. Meyer-Breiting E, Burkhart A. Unusual, malignant tumours.Chondrosarcoma. En: Burkhardt A, Meyer-Breiting E, editores.Tumours of the larynx. Histopathology and clinicalinferences. Berlin: Springer, 1998; 157-8.

7. Landaeta-Vilela JG, Muñoz-Chirino JG, Cardozo-RamonesVD, Ramones-De Cardozo EM. Condrosarcoma de laringe:Revisión de la literatura y presentación de un caso. RevVenez Oncol 2005; 17 (1): 51-55.

8. Gadwal SR, Fanburg-Smith JC, Gannon FH, Thompson LD.Primary chondrosarcoma of the head and neck in pediatricpatients: a clinicopathologic study of 14 cases with a reviewof the literature. Cancer 2000; 88 (9): 2181- 2100.

9. Sociedad Americana De Cáncer. ¿Qué es cáncer de hueso?Equipo de redactores y equipo de editores médicos de laSociedad Americana contra el Cáncer. 2018. Disponible en:¿Qué es el cáncer de hueso? (cancer.org)

10. Chin OY, Dubal PM, Sheikh AB, Unsal AA, Park RC, BaredesS, Eloy JA. Laryngeal chondrosarcoma: A systematic reviewof 592 cases. Laryngoscope 2017; 127 (2): 430-439. doi:10.1002/lary.26068.

11. Martínez-Tello FJ. Condrosarcoma. Variantes de condrosarcoma.Rev Esp Patol 2006; 39 (2): 69-79.

12. Villar-Kuscevic D, López-Soto D, Villar-Benavides A. Condrosarcomalaríngeo. Rev Cubana Otorrinolaringología yCirugía de Cabeza y Cuello 2013; 1 (2).

13. Buda I, Hod R, Feinmesser R, Shvero J. Chondrosarcoma ofthe larynx. Isr Med Assoc J 2012; 14 (11): 681-684.

14. Sakai O, Curtin DH, Faquin CW, Fabian LR. Dedifferentiatedchondrosarcoma of the larynx. Am J Neuroradiol 2000;21: 584-586.

15. Tachino H, Fushiki H, Ishida M, Watanabe Y. A low-gradechondrosarcoma presenting as an unusual cervical massin the hyoid bone: a case report. J Med Case Rep 2012; 6:21. doi: 10.1186/1752-1947-6-21.

16. Saleh HM, Guichard C, Russier M, Kémény JL, Gilain L.Laryngeal chondrosarcoma: a report of five cases. EurArch Otorhinolaryngol 2002; 259 (4): 211-6. doi: 10.1007/s00405-001-0434-x.

17. Moen CM, Lim AE, Townsley RB. Low-grade chondrosarcomaof the posterior cricoid plate. Cureus 2021; 13 (6):e15400. DOI: 10.7759/cureus.15400.