Contreras-Tovar PS, Alvarado-Campos E, Montes OLF, Escudero-Tepale EM

Language: Spanish
References: 15
Page: 103-109
PDF size: 310.27 Kb.

ABSTRACT

The eosinophilic granulomatosis with polyangiitis (EGP), also called Churg-Strauss syndrome, is a systemic disorder of unknown etiology. It is characterized by necrotizing vasculitis affecting small- and medium-sized vessels, with multiple systemic manifestations. Eosinophilic vasculitis can affect numerous organs and systems, including the integumentary, nervous, pulmonary, cardiovascular, gastrointestinal, and renal systems. EGP is a rare disease with an incidence ranging from 2.4 to 4 cases/million inhabitants/year in the general population. This article presents a clinical case of a 63-year-old man with EGP. Currently, there are very few reports of Mexican patients with this disease. Notably, those reports have described that the initial presentation is usually in the respiratory tract, whereas the damage to the peripheral nervous system is a sequela. To our knowledge, our patient is the first case in Mexico presenting rapidly progressive peripheral neuropathy symptoms as the initial manifestation. Moreover, the patient does not present asthma, which nearly all EGP patients exhibit. In this regard, it is imperative to highlight that, although peripheral neuropathy does not usually affect the survival of patients, the damage is generally permanent and can cause physical disability, significantly impairing their quality of life. Therefore, timely diagnosis and treatment are essential.

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