2021, Number 2
Biopsia de Ganglio Centinela en Cáncer de mama. Valoración en el Instituto Nacional de Oncología y Radiobiología. 2017-2019
Language: Spanish
References: 30
Page: 10-17
PDF size: 225.89 Kb.
ABSTRACT
Objective: To evaluate the effectiveness of the Selective Sentinel Lymph Node Biopsy technique in patients with breast cancer.Materials and methods: A retrospective-prospective descriptive study, of the case series type, was carried out in 199 patients with breast cancer admitted and operated on during the period from January 2017 to December 2019 in the Mastology Service of the National Institute of Oncology and Radiobiology. Analysis of the variables was carried out and the information was recorded in an Excel database, with which the tables were created to analyze the characteristics of the analyzed technique.
Results: The age group of 51 to 60 years predominated, the most frequent location of the tumor on physical examination was in the right breast, the predominant clinical stage was IIA, and the most frequent histological type was infiltrating ductal carcinoma. The sentinel node biopsy techniques used were with dye, radiopharmaceutical and mixed, yielding an identification rate of the detected nodes of 92.5% and the highest number of identified nodes was two nodes. In addition, the surgical techniques that were used were Conservative Surgery, Modified Radical Mastectomy and others using breast reconstruction techniques.
Conclusions: The Selective Sentinel Lymph Node Biopsy technique was effective in the axillary evaluation of patients with breast cancer who fulfilled the criteria for its application.
REFERENCES
Rebollo-Aguirre ÁC, Gallego-Peinado M, Menjón-Beltrán S, García-García J, Pastor-Pons E, Chamorro-Santos CE, et al. Sentinel lymph node biopsyin patients with operable breast cancer treated with neoadjuvant chemotherapy. [Internet] 2012 Revista española de Medicina Nuclear e ImagenMolecular [citado mar 12 2020] 31(3):117-123. Disponible https://www.sciencedirect.com/science/article/abs/pii/S2253808912000481en:
Senkus E, Kyriakides S, Penault-Llorca F, Poortmans P, Thompson A, Zackrisson S, et al. Primary breast cancer: ESMO clinical practiceguidelines for diagnosis, treatment and follow-up. [Internet] 2013. Ann Oncol; [citado mar 12 2020] 24(SUPPL.6):vi7-vi23. Disponible en:https://pubmed.ncbi.nlm.nih.gov/23970019/
Díaz Expósito, Rafael. Biopsia selectiva del Ganglio Centinela en pacientes con cáncer de mama. Efecto de la quimioterapia neo adyuvantey grado de respuesta clínica y patológica. Tesis Doctoral. Hospital Universitario de Valencia, España. [Internet] 2015 [citado enero 12 2019] 94-113. Disponible en: https://www.tdx.cat/handle/10803/570795
Çolakoğlu MK, Güven E, Akgül GG, Doğan L, Gülçelik MA. Biological Subtypes of Breast Cancer and Sentinel Lymph Node Biopsy. [Internet]2018 Eur J Breast Health; [citado mar 12 2020] 14: 100-104. Disponible en: https://www.eurjbreasthealth.com/en/biological-subtypes-ofbreast-cancer-and-sentinel-lymph-node-biopsy-13610
Lale A et al., Predictors of non-sentinel lymph node metastasis in clinical early stage (cT1-2cN0) breast cancer patients with 1/2 metastaticsentinel lymph nodes, [Internet] 2019 Asian Journal of Surgery, [citado mar 12 2020] https://doi.org/10.1016/j.asjsur.2019.07.019 Disponibleen: https://www.researchgate.net/publication/335727751_Predictors_of_non-sentinel_lymph_node_metastasis_in_clinical_early_stage_cT1-2N0_breast_cancer_patients_with_1-2_metastatic_sentinel_lymph_nodes
Seung AL, Lee HM, Lee HW, Yang BS, Park JT, Ahn SG, et al. Risk Factors for a False-Negative Result of Sentinel Node Biopsy in Patientswith Clinically Node-Negative Breast Cancer. [Internet] 2018 Cancer Res Treat. [citado mar 12 2020] 50(3):625-633. Disponible en: https://pubmed.ncbi.nlm.nih.gov/28759990/
Hellingmana D, Wana OY, de Wit-van der Veena BJ, van der Ploegb IM, Elkhuizenc PHM, Rutgersb EJTh et al. Predictive risk factors forsentinel lymph node nonvisualization on planar lymphoscintigraphy using an intratumoral injection in patients with primary breast cancer.[Internet] 2019 Nuclear Medicine Communications 2019, [citado mar 12 2020] Vol 40 No 4 Disponible en: https://www.google.com/search?q=Hellingmana+D,+Wana+OY,+de+Wit-
Domínguez Cunchillos F, Ballester Sapiña JB, de Castro Parga G. Guías Clínicas dela Asociación Española de Cirujanos. Cirugía de la mama. Sección de Patología de la Mama [Internet] 2017. Arán Ediciones, S.L. ISBN 1.ªEdición: 978-84-95913-97-5ISBN 2.ª Edición: 978-84-17046-18-7 [citado mar 12 2020] Disponible en: https://www.aecirujanos.es/files/documentacion/documentos/cirugia-mama.pdf
Sociedad Argentina de Mastología, Asociación Argentina de Oncología Clínica, Asociación Argentina de Ginecología Oncológica. SociedadArgentina de Cancerología, Sociedad Argentina de Terapia Radiante Oncológica, Instituto de Oncología “Ángel Roffo” Consenso sobre gangliocentinela positivo en estadios iniciales de cáncer de mama [Internet] 2019. [citado sept 20 2020] Disponible en: https://www.samas.org.ar/archivos/centinelapos.pdf
R. Ruano Péreza, A.C. Rebollo Aguirre, P. García-Talavera San Miguel, R. Díaz Expósito, S. Vidal-Sicarte, J.M. Cordero García, et al., Grupo deTrabajo de Cirugía Radioguiada de la SEMNIM. Actualización de la biopsia del ganglio centinela tras quimioterapia neoadyuvante en el cáncer demama sin y con afectación ganglionar al diagnóstico. [Internet] 2018 Revista Española de Medicina Nuclear e Imagen Molecular. [citado sept 202020] Vol. 37. Núm. 1.Páginas 63-70 (Enero-Febrero) Disponible en: https://www.elsevier.es/es-revista-revista-espanola-medicina-nuclear-e-125-articulo-actualizacion-biopsia-del-ganglio-centinela-S2253654X17300963?referer=coleccion
Gonzáles Espinosa C, Valdés Guerrero O, Campos Bernardo MC, Calderón Marín C, Mestre Fernández BF. Implicancias de la biopsia selectivade ganglio centinela en cadena mamaria interna en el cáncer de mama. [Internet] 2020 Acta Med Peru. 37(2):204-8. [citado sept 20 2020]Disponible en: http://www.scielo.org.pe/pdf/amp/v37n2/1728-5917-amp-37-02-204.pdf
Daniel Mysler, Federico Andres Coló, Cristina Noblia, Gustavo Hauszpigiel Consenso sobre Ganglio Centinela positivo en estadios inicialesCáncer de Mama. Instituto Alexander Fleming. Universidad de Buenos Aires. [Internet] 2020 [citado sept 20 2020] Disponible en. https://www.researchgate.net/publication/324546373_Consenso_sobre_Ganglio_Centinela_positivo_en_estadios_iniciales_Cancer_de_Mama