2021, Number 2
Deterioro cognitivo en pacientes con enfermedad de Parkinson
Language: Spanish
References: 17
Page: 280-287
PDF size: 387.20 Kb.
ABSTRACT
Introduction: Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder. The presence of cognitive impairment is one of the non-motor symptoms that a patient with Parkinson's disease may present; it is very important because it affects, in particular, executive, attentional, visuospatial and memory domains.Objective: to determine the relationship between the presence of cognitive impairment and the clinical characteristics of patients with Parkinson's disease belonging to the Municipality of Cifuentes.
Methods: a descriptive, cross-sectional, observational study was carried out in the health areas of Cifuentes from October 2013 to October 2019. The study population consisted of 34 patients, the population coincides with the study sample.
Results: 76.47% of the study patients presented cognitive impairment compared to 64.70% of the patients who were found to be cognitively impaired (according to the clock drawing test). A trend is observed, both with the Movement Disorder Society-Unified Parkinson's Disease Rating Scale and with the Hoehn and Yarh scale, that the greater the degree of severity, the greater the prevalence of cognitive impairment.
Conclusions: patients between 61 and 70 years of age and male sex have a higher risk of developing Parkinson's disease. According to the clock drawing test and the mini- mental state examination, patients with Parkinson's disease with cognitive impairment predominated. There was a tendency that the higher the degree of severity, the higher the prevalence of cognitive impairment.
REFERENCES
Aarsland D, Creese B, Politis M, Chaudhuri KR, Fytche DH, Weintraub D, et al. Cognitive decline in Parkinson disease. Nat Rev Neurol [Internet]. 2017 Apr [citado 15/03/2019];13(4):217-31. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643027/. https://dx.doi.org/10.1038/nrneurol.2017.27
Galtier I, Nieto A, Lorenzo JN, Barroso J. Mild cognitive impairment in Parkinson’s disease: Diagnosis and progression to dementia. J Clin Exp Neuropsychol [Internet]. 2016 Nov [citado 15/03/2019];38(1):40-50. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26602176/. https://doi.org/10.1080/13803395.2015.1087465
GBD 2016 Neurology Collaborators. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol [Internet]. 2019 May [citado 15/03/2019];18(5):459-480. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459001/. https://dx.doi.org/10.1016/S1474-4422(18)30499-X
Winter Y, von Campenhausen S, Arend M, Longo K, Boetzel K, Eggert K, et al. Health-Related Quality of Life and Its Determinants in Parkinson’s Disease: Results of an Italian Cohort study. Parkinsonism & Related Disorders [Internet]. 2011 May [citado 15/03/2019];17(4):265–9. Disponible en: https://www.scirp.org/(S(351jmbntvnsjt1aadkposzje))/reference/ReferencesPapers.aspx?ReferenceID=1211288. http://dx.doi.org/10.1016/j.parkreldis.2011.01.003
Erro R, Stamelou M. Chapter Two - The Motor Syndrome of Parkinson’s Disease. En: Bhatia KP, Chaudhuri KR, Stamelou M, editores. Int Rev Neurobiol [Internet]. 2017 [citado 27/06/2018];132:25-32. Disponible en: http://www.sciencedirect.com/science/article/pii/S0074774217300041. https://doi.org/10.1016/bs.irn.2017.01.004
Cuba. Ministerio de Salud Pública. Dirección Nacional de Registros Médicos y Estadística de Salud. Anuario Estadístico de Salud 2018 [Internet]. La Habana: MINSAP; 2019 [citado 22/05/2019]. Disponible en: http://files.sld.cu/bvscuba/files/2019/04/Anuario-Electr%C3%B3nico-Espa%C3%B1ol-2018-ed-2019.pdf
Teodoro T, Edwards MJ, Isaacs JD. A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome: systematic review. J Neurol Neurosurg Psychiatry [Internet]. 2018 Dic [citado 13/05/2019];89(12):1308-19. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288708/. https://dx.doi.org/10.1136/jnnp-2017-317823
Rodríguez Violante M, Villar Velarde A, Valencia Ramos C, Cervantes Arriaga A. Características epidemiológicas de pacientes con enfermedad de Parkinson de un hospital de referencia en México. Arch Neurocien (Mex) [Internet]. 2011 [citado 15/05/2019];16(2):64-68. Disponible en: https://www.medigraphic.com/pdfs/arcneu/ane-2011/ane112d.pdf
Diazgranados Sánchez JA, Chan Guevara L, Gómez Betancourt LF, Lozano Arango AF,Ramirez M. Descripción de la población de pacientes con enfermedad de Parkinson en un centro médico neurológico en la ciudad de Cali, Colombia. Acta Neurol Colomb [Internet]. 2011 [citado 15/05/2019];27(4):205-210. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-87482011000400003
Cereda E, Cilia R, Klersy C, Siri C, Pozzi B, Reali E, et al. Dementia in Parkinson’s disease: Is male gender a risk factor? Parkinsonism Relat Disord [Internet]. 2016 May [citado 15/05/2019];26:67-72. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26952697/. https://doi.org/10.1016/j.parkreldis.2016.02.024
Isais Millán S, Piña Fuentes D, Guzmán Astorga C, Cervantes Arriaga A, Rodríguez Violante M. Prevalencia de trastornos neuropsiquiátricos en pacientes con enfermedad de Parkinson (EP) no tratados. Gac Med Mex [Internet]. 2016 [citado 15/05/2019];152(3):357-63. Disponible en: https://www.medigraphic.com/pdfs/gaceta/gm-2016/gm163l.pdf
Pfeiffer HCV, Lokkegaard A, Zoetmulder M, Friberg L, Werdelin L. Cognitive impairment in early-stage non-demented Parkinson’s disease patients. Acta Neurol Scand [Internet]. 2014 May [citado 15/05/2019];129(5):307-18. Disponible en: https://pubmed.ncbi.nlm.nih.gov/24117192/. https://doi.org/10.1111/ane.12189