2022, Number 2
<< Back Next >>
Dermatología Cosmética, Médica y Quirúrgica 2022; 20 (2)
Squamous cell carcinoma associated with alopecic plaque of lichen planus pilar
Alvarado-Delgadillo A, Esquivel-Pinto IA, Ramírez-González JY
Language: Spanish
References: 10
Page: 169-172
PDF size: 791.99 Kb.
ABSTRACT
Lichen planus pilaris (LPP) was first described by Pringle in 1895.
The etiology of lichen planus pilaris is still not well understood,
but it represents one of the main causes of cicatricial alopecia.
Association of malignant neoplasms such as squamous cell carcinoma
has been reported in patients with oral lichen planus
and less frequently in cutaneous lichen planus, however reports
in lichen planus pilar are isolated.
We present the case of a 52-year-old male patient with
20-year-old history of cicatricial alopecia due to lichen planus
pilar with development of squamous cell carcinoma (SC)
in situ
on alopecic plaque.
It is important to consider that the association of very longstanding
LPP and the development of SC may be related to the
chronic inflammatory process of the LPP and the increased exposure
to solar radiation in alopecic plaques.
REFERENCES
Brankov N, Conic RZ, Atanaskova-Mesinkovska N, Piliang M y BergfeldW, Comorbid conditions in lichen planopilaris: a retrospectivedata analysis of 334 patients, Int J Women’s Dermatology 2018; 4(3):180-4. Disponible en: https://doi.org/10.1016/j.ijwd.2018.04.001.
Cevasco NC, Bergfeld WF, Remzi BK y De Knott HR, A case-series of29 patients with lichen planopilaris: the Cleveland Clinic Foundationexperience on evaluation, diagnosis, and treatment, J Am Acad Dermatol2007; 57(1):47-53. doi: 10.1016/j.jaad.2007.01.011.
Soares VC, Mulinari-Brenner F y Souza TE, Lichen planopilarisepidemiology: a retrospective study of 80 cases, An Bras Dermatol2015; 90(5):666-70. Disponible en: https://doi.org/10.1590/abd1806-
4841.20153923.4. Du X, Li Y, Zhu Q, Zhu J, Xu W, Li Z y Elston DM, Focal and diffuse fibrosingalopecias: classical lichen planopilaris, frontal fibrosing alopecia,fibrosing alopecia with a pattern distribution, cicatricial pattern hairloss, and lichen planopilaris diffuse pattern, J Am Acad Dermatol 2020;6(5):403-10. Disponible en: https://doi.org/10.1016/j.jdcr.2020.02.036.
Anzai A, Wang E, Lee EY, Aoki V y Christiano AM, Pathomechanismsof immune-mediated alopecia, Int Immunol 2019; 31(7):439-47. Disponibleen: https://doi.org/10.1093/intimm/dxz039.
Van de Maele B, Vossaert K, Lanssens S, Haspeslagh M y De SchepperS, Facial lichen planopilaris: a separate entity or not? A case series, IntJ Trichology 2018; 10(4):183-5. Disponible en: https://doi.org/10.4103/ijt.ijt_5_18.
Garrido CC, Castro A, Valenzuela I, Martínez GE, Blasco MG y TercedorSJ, Squamous cell carcinoma in lichen planopilaris, J DermatolCase Rep 2013; 7(3):84-7. Disponible en: https://doi.org/10.3315/jdcr.2013.1147.
Tang L y Wang K, Chronic inflammation in skin malignancies, J MolSignal 2016; 11(1):2. Disponible en: https://doi.org/10.5334/1750-2187-11-2.
Iamsumang W, Rutnin S y Suchonwanit P, Comedone-like lesions as amanifestation of lichen planopilaris beyond the scalp: a case report withdermoscopic features and literature review, Case Reports in Dermatolog2021; 13(1):106-13. Disponible en: https://doi.org/10.1159/000512711.
Grivennikov SI, Greten FR y Karin M, Immunity, inflammation, and cancer,Cell 2010; 140(6):883-99. Disponible en: https://doi.org/10.1016/j.cell.2010.01.025.