2022, Number 2
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Dermatología Cosmética, Médica y Quirúrgica 2022; 20 (2)
Alopecia areata universalis treated with oral pulse of dexamethasone. A case report
Vera RV, Arrazola MKS
Language: Spanish
References: 15
Page: 143-147
PDF size: 428.86 Kb.
ABSTRACT
Alopecia areata is an autoimmune disease that results in nonscarring
hair loss, clinically characterized by small patches of
baldness isolated or confluent, it can later progress to total loss
of scalp hair (alopecia totalis) or total loss of all hair body (alopecia
universalis) which can affect beard, underarm hair, pubic
or any hair-bearing sites.
We report a 22-year-old female patient who consulted
with alopecic areas on the scalp, eyelashes, armpits, pubis, and
upper and lower limbs. According to the clinical, trichoscopic
and interrogation characteristics, alopecia areata universalis was
diagnosed and treatment was started with pulses of oral dexamethasone,
with a total regrowth of the alopecic areas.
REFERENCES
Simakou T, Butcher JP, Reid S y Henriquez FL, Alopecia areata: a multifactorialautoimmune condition, J Autoimmun 2019; 98:74-85.
Strazzulla LC, Wang EHC, Ávila L, Lo Sicco, Brinster N, Christiano AMet al., Alopecia areata. Disease characteristics, clinical evaluation andnew perspectives on pathogenesis, J Am Acad Dermatol 2017; 78:1-12.
Lee S y Lee WS, Management of alopecia areata: updates and algorithmicapproach, J Dermatol 2017; 44:1199-211.
Pratt CH, King LE, Messenger AG, Christiano AM y Sundberg JP, Alopeciaareata, Nat Rev Dis Primers 2017; 03:1-17.
Burroway B, Griggs J y Tosti A, Alopecia totalis and universalis longtermoutcomes: a review, J Eur Acad Dermatol Venereol 2020; 34:709-15.
Was´kiel A, Rakowska A, Sikora M, Olszewska M y Rudnicka L, Trichoscopyof alopecia areata: an update, J Dermatol 2018; 45:692-700.
MacDonald HSP, Wood ML, Hutchinson PE, Sladden M y MessengerAG, Guidelines for the management of alopecia, Br J Dermatol 2003;149:692-9.
Rossi A, Muscianese M, Piaraccini B, Starace M, Carlesimo M, ManderlV et al., Guidelines in diagnosis and treatment of alopecia areata, G ItalDermatol Venereol 2019; 154:609-23.
Kassira S, Korta DZ, Chapman LW y Dann F, Review of treatment foralopecia totalis and alopecia universalis, Int J Dermatol 2017; 56: 801-10.
Strazzulla LC, Wang EHC, Ávila L, Lo Sicco, Brinster N, Christiano AMet al., Alopecia areata. An appraisal of new treatment approaches andoverview of current therapies, J Am Acad Dermatol 2018; 78:15-24.
Jabbari A, Sansaricq F, Cerise J, Chen JC, Bitterman A, Ulerio G et al.,An open-label pilot study to evaluate the efficacy of tofacitinib inmoderate to severe patch-type alopecia areata, totalis, and universalis,J Invest Dermatol 2018; 138:1539-45.
Liu LY, Craiglow BG, Dai F y King BA, Tofacitinib for the treatment ofsevere alopecia areata and variants: a study of 90 patients, J Am AcadDermatol 2017; 76:22-8.
Galán-Gutiérrez M, Rodríguez-Bujaldón A y Moreno-Giménez C, Actualizaciónterapéutica en alopecia areata, Actas Dermosifiliogr 2009;100:266-76.
Vañó-Galván S, Hermosa-Gelbard A, Sánchez-Neila N, Miguel-GómezL, Saceda-Corralo D, Rodrigues B et al., Pulse corticosteroid therapywith oral dexamethasone for the treatment of adult alopecia totalisand universalis, J Am Acad Dermatol 2016; 74:1005-7.
Sharma VK y Gupta S, Twice weekly 5 mg dexamethasone oral pulsein the treatment of extensive alopecia areata, J Dermatol 1999; 26:562-5.