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2021, Number 1

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Finlay 2021; 11 (1)

Congenital bullous epidermolysis. Clinical update

Vázquez NMA, Santiesteban ARE, Ferrer MYI

Language: Spanish
References: 16
Page: 74-79
PDF size: 113.28 Kb.


ABSTRACT

Bullous epidermolysis is an inherited, chronic, incurable and low prevalence disease. It is characterized by the appearance of blisters after minimal trauma, predominantly cutaneous and difficult to manage. It is caused by mutations in various genes that code for dermoepidermal junction proteins, which leads to the formation of blisters and erosions, in addition to multiple other systemic alterations. There are three large groups depending on the genetic mutation. For its diagnosis, a skin biopsy is performed. There is no effective treatment, the most commonly used treatments being symptomatic and palliative. Congenital bullous epidermolysis is a rarely observed disease, for this reason it is a medical challenge to go from syndromic to specific diagnosis. In this sense, the objective of this work is to describe the main characteristics of bullous epidermolysis. A total of 15 bibliographies were reviewed.


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