2021, Number 1
<< Back Next >>
Rev Cub de Reu 2021; 23 (1)
Tumor of giant cells of the femur. Case presentation
León AP, Pila PR, Rosales TP
Language: Spanish
References: 13
Page: 1-8
PDF size: 432.80 Kb.
ABSTRACT
Background: The giant cell tumor of bone is a rare benign tumor with a locally aggressive behavior. It predominates in women and usually occurs in the epiphysis and metaphysis of long bones.
Objective: To present a patient with a tumor lesion left knee and thigh two years of evolution, also noted the diagnostic characteristics of this tumor while recent imaging methods are reviewed for confirmation.
Case report: 19-year-old male who began with pain, increased volume of the knee and left thigh, accompanied by functional impotensia. clinical, radiological and histological findings were reported. Because of the delay between the onset of symptoms and diagnosis surgical treatment of the affected limb (amputation) was performed. After ten months of observation there have been no recurrences or metastases.
Conclusions: The giant cell tumor of bone is a rare tumor with good prognosis but can recur and metastasize when it becomes malignant. The possibility of transformation in sarcoma requires periodic study and observation. The time for diagnosis is essential and should think of this tumor in case of lytic bone lesions reported by imaging.
REFERENCES
Jaffé H, Lichtenstein S, Portis R. Giant cell Tumor of bone. Arch Pathol. 1940; 30: 993-1031.
Pila Pérez R, Pila Pelaéz R, Rosales Torres P, Holguín Prieto V. Tumor de células gigantes de hueso y manifestaciones paraneoplásicas. Comunicación de un caso. Mapfre Medicina. 2007; 18(1): 36-41.
Lopez-Pousa A, Brotó JM, Garrido T, Vázquez. Giant cell tumor of bone: new treatments in development. Clin Transl Oncol. 2015; 17: 419-30.
Enneking W. Musculoskeletal Tumor surgery, New York: ed Churchill; Livingstone; 1983.
Vaidya K, Sarode GS, Sarode SC, Majumdar B, Patil S. Peripheral giant cell granuloma recurring as an exclusively intraosseous lesion: An unusual clinical presentation. Clin. Pract. 8(1):1023-2018.
Aarcón A, Muñoz R M, Schetner K, Ulloa MC. Peripheral giant cell granuloma and hyperparathyroidism. Case report. Int. J. Odontostomat. 2019;13(3):266-70.
Consoli NR, Berardi AG, Pasquale NV, Pesce MA, De Franceschi C. Granuloma central de células gigantes. Caso clínico y tratamiento quirúrgico. Rev Asoc Odontol Argent. 2018;106:93-7.
Loquercio G, Di Costanzo G, Fazioli F, Gallo M, De Chiara A, Lervolino V, et al. Autologous platelet gel improves bone reconstruction of large defects in patients with bone giant cell tumors. In Vivo. Sept-Oct. 2015;29(5):533-40.
Rajani R, Schaefer L, Scarborough MT, Gibbs CP. Giant cell tumors of the foot and ankle bones: high recurrence rates after surgical treatment. J Foot Ankle Surg. NovDec. 2015;54(6):1141-5
Wysocki RW, Soni E, Virkus WW, Scarborough MT, Leurgans SE, Gitelis S. Is intralesional treatment of giant cell tumor of the distal radius comparable to resection with respect to local control and functional outcome? Clin Orthop Relat Res. 2015;473(2):706-15.
Cheng DD, Hu T, Zhang HZ, Huang J, Yang QC. Factors affecting the recurrence of giant cell tumor of bone after surgery: A clinicopathological study of 80 cases from a single center. Cell Physiol Biochem. 2015;36(5):1961-70.
Niu X, Xu H, Inwards CY, Li Y, Ding Y, Letson GD, et al. Primary Bone Tumors: Epidemiologic comparison of 9 200 patients treated at Beijing Ji Shui Tan Hospital, Beijing, China, with 10 165 patients at MayoClinic, Rochester, Minnesota. Arch Pathol Lab Med. 2015;139(9):1149-55.
Chan CM, Adler Z, Reith JD, Gibbs CP. Risk factors for pulmonary metastases from giant cell tumor of bone. J Bone Joint Surg Am. 2015;97(5):420-8.