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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2022, Number 2

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An Med Asoc Med Hosp ABC 2022; 67 (2)

Post oocyte capture hemorrhage in a patient with hemophilia-b (Christmas disease)

Muńoz CFJM, Ruiz LR, Chávez SJG, Álvarez VR

Language: Spanish
References: 16
Page: 152-155
PDF size: 232.78 Kb.


ABSTRACT

Hemophilia is a recessive hereditary coagulation disorder linked to the X chromosome. It is rare and mainly affects men, women are considered carriers and therefore, in most cases, do not have symptoms associated with bleeding. Only 3.2% of individuals clinically affected by hemophilia-B are women. This is due to the lionization phenomenon in which an X chromosome is suppressed randomly, causing a small number of patients to have a decreased percentage of activity in coagulation factors. We present the case of a 27-year-old woman with mild coagulation factor IX deficiency (Christmas disease) who presents with post-surgical hemorrhage after an oocyte capture for an in vitro fertilization treatment. The purpose of this article is to raise awareness about coagulation disorders in women with abnormal bleeding or family history. Timely diagnosis reduces the risk and incidence of bleeding in the peri-operative period of women who are not yet diagnosed with hemophilia.


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