2022, Number 2
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Rev Med UAS 2022; 12 (2)
Concordance between clinical and histopathological diagnosis of skin melanoma
Martínez-Félix M, Calzada-Pedroza Á, Moran-Portela DJ, Merino-Ramírez JF, Lizárraga-Verdugo E, Becerril-Camacho DM, Ríos-Burgueño ER
Language: Spanish
References: 14
Page: 116-123
PDF size: 602.53 Kb.
ABSTRACT
Objective: To determine the concordance between the clinical and/or histopathological diagnosis of skin melanoma.
Methodology: A series of cases of patients with clinical and/or histopathological diagnosis of cutaneous melanoma treated in the department of dermatology and the samples were analyzed in the department of pathological anatomy from January 2015 to December 2019 in the HCC was conducted.
Results: The concordance between the clinical diagnosis for skin melanoma compared to the gold standard (histopathological result for melanoma) was 31.1% (n = 14), while the discrepancy between the clinical and histopathological diagnosis for cutaneous melanoma observed was of 51.1% (n = 23), and for non-melanoma it was 15.6% (n = 7). Cohen's Kappa index -0.278 (-27.8%), statistical significance p = 0.011. χ
2 1gl 0.05 = 6.51, p = 0.01.
Conclusions: In this study, the clinical diagnosis of cutaneous melanoma presented a low concordance with the histopathological study. We consider that, in subsequent studies, a larger number of samples and dermoscopy could be useful to have a better clinical-histopathological agreement.
REFERENCES
McKee PH, Calonje E, Lazar A, Brenn T. Melanoma In McKee's Pathology of the Skin: With Clinical Correlations. 1. 4th ed: Elsevier Saunders; 2012. p. 1221-67.
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Esti-mates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209-49.
Prevención primaria y detección oportuna del melanoma cutáneo en población general en el primer nivel de atención médica. México: Secretaría de Salud; 03/11/2016.
Tsao H, Olazagasti JM, Cordoro KM, Bre-wer JD, Taylor SC, Bordeaux JS, et al. Early detection of melanoma: reviewing the ABCDEs. J Am Acad Dermatol. 2015 Apr 1;72(4):717-23.
Villalobos LML, Molina VR, López GJL, Ál-varez-Mon SM. Melanoma. Medicine. 2013;11(26):1597-607.
Crowson AN, Magro CM, Mihm MC. An Ap-proach to the Clinical Diagnosis of Mela-noma, Its Precursors, and Its Clinical Mimics In: John Wiley & Sons I, editor. The Melano-cytic Proliferations: A Comprehensive Text-book of Pigmented Lesions. 2nd ed. New Jersey: John Wiley & Sons, Inc.; 2014. p. 1-42.
Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, Washington MK, et al. (Eds.). AJCC Cancer Staging Manual. 8th ed: Springer International Publishing: American Joint Commission on Cancer; 2017. p. 563-87.
Patrawala S, Maley A, Greskovich C, Stuart L, Parker D, Swerlick R, et al. Discordance of histopathologic parameters in cutaneous melanoma: Clinical implications. J Am Acad Dermatol. 2016;74(1):75-80.
Basko-Plluska JL, Prieto VG, Reed JA, Shea CR. Clinicopathologic Correlation in Melanocytic Lesions. Pathology of Challen-ging Melanocytic Neoplasms. New York: Springer Science+Business Media; 2015. p. 180.
Bush JW, Hunt EL, Fraga GR. BAM Utilizing the frequency of Benign, Atypical and Malig-nant diagnoses for quality improvement in the histopathologic diagnosis of melanocytic neoplasms. J Cutan Pathol. 2015;42:712–6.
Rosas S, Baca T, Muñoz D, Muñoz F, Mu-ñoz G. Estudio Clínico, Epidemiológico e Histopatológico de Melanoma Maligno: Se-rie de 31 casos. CIMEL 2003; 8(1): 23-27.
Pozzobon FC, Acosta AE. Epidemiological profile of primary cutaneous melanoma over a 15-year period at a private skin cancer center in Colombia. Rev Salud Publica (Bo-gota). 2018;20(2):226-31.
Káram-Orantes M, Toussaint-Caire S, Do-mínguez-Cherit J, Veja-Memije E. Caracte-rísticas clínicas e histopatológicas del mela-noma maligno en el Hospital General “Dr. Manuel Gea González”. Gac Méd Méx. 2008; 144(3): 219-223.
Šitum M, Buljan M, Kolić M, Vučić M. Mela-noma – Clinical, Dermatoscopical, and His-topathological Morphological Characteris-tics. Acta Dermatovenerol Croat. 2014;22(1):1-12.