Agudelo-Sanabria MB, Rozo-Ortiz EJ, Vargas-Rodríguez LJ

Language: Spanish
References: 10
Page: 718-721
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ABSTRACT

Background: Madelung’s disease is also known as multiple symmetric lipomatosis, benign symmetric lipomatosis, and Launois-Bensaude syndrome. It is a rare disorder characterized by a progressive, excessive and symmetrical accumulation of adipose tissue in the subcutaneous layer.
Clinical case: A 58-year-old male with an 8-month evolution clinical picture consisting of the appearance of masses in different parts of the body and a considerable increase in the size of the gluteal region. He had a history of chronic alcoholism. On physical examination, accumulations of a smooth and painless consistency were observed on palpation on the external face of the arms and abdomen, and an increase in the size of the buttocks with fatty characteristics with a level of pain on palpation was also evident. The biopsy confirmed the presence of adipose tissue in the lesions and ruled out tumor infiltration, thus confirming Madelung’s syndrome.
Conclusions: Madelung’s syndrome is a low prevalence disease, which is associated with modifiable and non-modifiable risk factors, within the latter the patient in the case presented was exposed to alcoholism. This is a patient with phenotypic characteristics of Madelung syndrome, from whom other probable differential diagnoses were downloaded and diagnosis was confirmed by histopathological study.

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