2022, Number 3
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Med Int Mex 2022; 38 (3)
Clinical and immunological characteristics of systemic lupus erythematosus applying the classification criteria of EULAR/ACR 2019
Renée SD, Mercado U
Language: Spanish
References: 12
Page: 507-513
PDF size: 188.39 Kb.
ABSTRACT
Objetivo: To describe the frequency and the clinical and immunological characteristics
of systemic lupus erythematosus applying the 2019 EULAR/ACR classification
criteria.
Materials and Method: A retrospective study was done describing the frequency
and the clinical and immunological characteristics of patients with systemic lupus
erythematosus care in the internal medicine and rheumatology service from 2014
to 2020. The cut-off points for the individual diagnosis of lupus was ≥ 10 points. The
presence of antinuclear antibodies was mandatory.
Results: There were included 132 patients, 116 women and 16 men with a 7:1 ratio.
The median age was 35 years (range: 12 to 58); 77% had arthritis, 71% leukopenia,
59% acute cutaneous lupus, 41% oral ulcers and 32% fever. Nephropathy was observed
in 28%, determined by proteinuria or renal biopsy; in 13 cases the histopathological
study revealed type III/IV nephritis and in one case type II/V nephritis (ISN/RPS); 78%
had anti-DNA native and 20% anti-Sm/RNP. The decrease in complement was found
in 22% of the cases.
Conclusions: The new classification criteria of EULAR/ACR 2019 for systemic lupus
erythematosus are based on previous criteria, except for fever. All our patients fulfilled
10 or more points to meet the classification criteria.
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