2022, Number 3
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Rev Mex Anest 2022; 45 (3)
Role of hemodilution in postoperative infections in patients undergoing cardiac surgery
Santiago-López J, León-Ramírez V, Pérez-Maldonado CI
Language: Spanish
References: 25
Page: 172-177
PDF size: 260.48 Kb.
ABSTRACT
Introduction: The impact on the immune system of normovolemic hemodilution as a perioperative blood-saving technique raises a possible increase in immunoglobulin M, and a possible increase in infections, especially those associated with catheters.
Objective: To compare the role of acute normovolemic hemodilution in postoperative infections in groups of patients undergoing cardiac surgery.
Material and methods: A controlled clinical trial in 99 patients undergoing elective cardiac surgery who were randomized into two groups: group I (non-hemodiluted) and group II (hemodiluted). The presence or absence of infection was determined during the postoperative period. Data analysis was performed using descriptive and inferential statistics χ
2. A p < 0.05 was considered significant. The data were processed using SPSS v.25.0.
Results: The overall incidence of infection was 3.03%. Hemodiluted patients became infected more frequently than non-hemodiluted patients. The isolated organisms were Escherichia coli and Enterobacter aerogenes.
Conclusion: Patients undergoing cardiac surgery who undergo acute normovolemic hemodilution suffer more frequently from postoperative infections than those who do not undergo acute normovolemic hemodilution.
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