Wegan-Hadad AS, Talayero-Petra JA, Larrea-Nájera A

Language: Spanish
References: 13
Page: 136-143
PDF size: 278.69 Kb.

ABSTRACT

Objective: To determine if the use of immunoglobulins and complement can be used as an indicator of severity in patients with obstructive sleep apnea-hypopnea syndrome.
Materials and Methods: Cross-sectional, observational, analytical study, which included patients aged 2 to 12 years, of both sexes and with a diagnosis of obstructive sleep apnea-hypopnea syndrome by polysomnography, treated from 2017 to 2020 in the Otorhinolaryngology Division of the General Hospital Dr. Manuel Gea González, Mexico City. The correlation analysis of the variables of interest was established by the Spearman Rho correlation test. 95% confidence interval (95% CI) was used as precision measures.
Results: There were included 23 patients. Spearman’s Rho nonparametric correlation was 0.53 for IgA, -0.1 for IgM, 0.38 for IgG, 0.31 for C3 and 0.02 for C4. The Pearson correlation test showed IgA of 0.64, IgM of -0.11, IgG of 0.17, C3 of 0.25 and C4 of -0.24.
Conclusions: Immunoglobulin A is positively correlated with the severity and index of obstructive sleep apnea-hypopnea; however, immunoglobulin and complement values cannot be used as an indicator of severity in pediatric patients with obstructive sleep apnea-hypopnea syndrome.

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