2022, Number 2
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Rev Mex Urol 2022; 82 (2)
Unusual cause of obstructive uropathy: a pelvic chondrosarcoma
Corona-Montes VE, Fernández-Noyola G, Chablé-Montero F, Cervantes-Sánchez AM, Cruz-Reyes C, Borja-Menéndez DA, Rosas-Nava JE, Sánchez-Núñez JE
Language: Spanish
References: 16
Page:
PDF size: 186.14 Kb.
ABSTRACT
We report the case of a 37-year-old male patient who
presented renal failure secondary to a pelvic tumor. The
diagnostic approach revealed a pubic-dependent tumor corresponding
to a mesenchymal chondrosarcoma that conditioned
obstructive uropathy as well as bladder and sigmoid
compression. Mesenchymal chondrosarcomas are soft tissue
dependent sarcomas with an extremely rare incidence,
the clinical importance of our report is due to the fact that
chondrosarcomas, must be considered in the differential
diagnoses of obstructive uropathy due to their compressive
effect on the urinary tract. We carry out a brief review
of diagnostic approach, therapeutic options and prognosis
of this pathology.
REFERENCES
Lichtenstein L, Bernstein D. Unusual benignand malignant chondroid tumors of bone. Asurvey of some mesenchymal cartilage tumorsand malignant chondroblastic tumors, includinga few multicentric ones, as well as many atypicalbenign chondroblastomas and chondromyxoidfibromas. Cancer. 1959;12(6):1142–57.doi: https://doi.org/10.1002/1097-0 1 4 2 (195911/12) 12: 6 < 1142:: AID-CNCR2820120610>3.0.CO;2-D
Lin O,, Zakowski MF. Cytology of SoftTissue, Bone, and Skin. In: ComprehensiveCytopathology. 3rd ed. Elsevier; 2008. p.Philadelphia.
Ghafoor S, Hameed MR, Tap WD, HwangS. Mesenchymal chondrosarcoma: imagingfeatures and clinical findings. SkeletalRadiol. 2021;50(2):333–41. doi: https://doi.org/10.1007/s00256-020-03558-x
Casali PG, Abecassis N, Bauer S, Biagini R,Bielack S, Bonvalot S, et al. Soft tissue andvisceral sarcomas: ESMO–EURACAN ClinicalPractice Guidelines for diagnosis, treatment andfollow-up†. Annals of Oncology. 2018;29:iv51–67. doi: https://doi.org/10.1093/annonc/mdy096
Wein AJ, M.D AWP, M.D LRK, Novick AC.Campbell-Walsh Urologia/ Campbell-WalshUrology. 11th ed. Ed. Médica Panamericana;2008. 808 p.
Xu J, Li D, Xie L, Tang S, Guo W. MesenchymalChondrosarcoma of Bone and Soft Tissue: ASystematic Review of 107 Patients in the Past 20Years. PLOS ONE. 2015 Apr 7;10(4):e0122216.doi: https://doi.org/10.1371/journal.pone.0122216
Frezza AM, Cesari M, Baumhoer D, Biau D,Bielack S, Campanacci DA, et al. Mesenchymalchondrosarcoma: prognostic factors andoutcome in 113 patients. A EuropeanMusculoskeletal Oncology Society study. Eur JCancer. 2015;51(3):374–81. doi: https://doi.org/10.1016/j.ejca.2014.11.007
Tsavaris O, Economopoulou P, Kotsantis I,Reppas L, Avgerinou C, Spathas N, et al. ClinicalBenefit of Pazopanib in a Patient with MetastaticChondrosarcoma: A Case Report and Review ofthe Literature. Frontiers in Oncology. 2018;8.doi: https://doi.org/10.3389/fonc.2018.00045
Nakashima Y, Unni KK, Shives TC, Swee RG,Dahlin DC. Mesenchymal chondrosarcomaof bone and soft tissue. A review of 111cases. Cancer. 1986;57(12):2444–53.doi: https://doi.org/10.1002/1097-0142 (19860615) 57: 12 < 2444 :: AIDCNCR2820571233>3.0.CO;2-K
Wang L, Motoi T, Khanin R, Olshen A, MertensF, Bridge J, et al. Identification of a novel,recurrent HEY1-NCOA2 fusion in mesenchymalchondrosarcoma based on a genome-widescreen of exon-level expression data. Genes,Chromosomes and Cancer. 2012;51(2):127–39.doi: https://doi.org/10.1002/gcc.20937
Shapeero LG, Vanel D, Couanet D, ContessoG, Ackerman LV. Extraskeletal mesenchymalchondrosarcoma. Radiology. 1993;186(3):819–26. doi: https://doi.org/10.1148/radiology.186.3.8430193
Mendenhall WM, Reith JD, ScarboroughMT, Stechmiller BK, Mendenhall NP.Mesenchymal Chondrosarcoma. Int J PartTher. 2016;3(2):300–4. doi: https://doi.org/10.14338/IJPT-16-00019.1
Tansir G, Rastogi S, Barwad A, Dhamija E. Longlasting response with trabectedin monotherapyin relapsed metastatic mesenchymalchondrosarcoma. Clinical Sarcoma Research.2020;10(1):16. doi: https://doi.org/10.1186/s13569-020-00138-4
Kawai A, Araki N, Sugiura H, Ueda T,Yonemoto T, Takahashi M, et al. Trabectedinmonotherapy after standard chemotherapyversus best supportive care in patients withadvanced, translocation-related sarcoma: arandomised, open-label, phase 2 study. LancetOncol. 2015;16(4):406–16. doi: https://doi.org/10.1016/S1470-2045(15)70098-7
Araki N, Takahashi S, Sugiura H, Ueda T,Yonemoto T, Takahashi M, et al. Retrospectiveinter- and intra-patient evaluation of trabectedinafter best supportive care for patients withadvanced translocation-related sarcoma afterfailure of standard chemotherapy. EuropeanJournal of Cancer. 2016;56:122–30. doi: https://doi.org/10.1016/j.ejca.2015.12.014
Cesari M, Bertoni F, Bacchini P, Mercuri M,Palmerini E, Ferrari S. Mesenchymal chondrosarcoma.An analysis of patients treated at asingle institution. Tumori. 2007;93(5):423–7.