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Federación Mexicana de Ginecología y Obstetricia, A.C.

2022, Number 05

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Ginecol Obstet Mex 2022; 90 (05)

Relationship between iron and gestational diabetes mellitus: a narrative review

Márquez-Ibarra AA, Mariscal-Ramírez BE, González-Ponce AM, Valbuena-Gregorio E

Language: Spanish
References: 34
Page: 434-442
PDF size: 223.34 Kb.


ABSTRACT

Objective: To evaluate the scientific evidence about the relationship between iron and gestational diabetes mellitus.
Methodology: Narrative review, based on the search for articles published from 2000 to 2021 in the PubMed, LILACS, BIREME, NICE, SIGN and CENETEC databases with the MeSH: Iron, iron and diabetes, Iron overland, Gestational Diabetes and Iron Overland and Gestational Diabetes. Those related to the topic of interest were selected.
Results: 119 articles were found and only 34 were considered adequate for the purpose of the review because they were directly related to iron metabolism, gestational diabetes and iron as a cause of gestational diabetes. Cross-sectional studies, cases and controls, cohorts, trials, reviews and meta-analyses were obtained.
Conclusions: The relationship between iron and gestational diabetes mellitus is not properly established; however, it has been related to the oxidative capacity of iron through different mechanisms that accentuate insulin resistance. It is suggested that high iron concentrations could be a risk factor for gestational diabetes mellitus.


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