Mellado-Orellana R, Ortega-Chavarría MJ, Rojas-Velasco G, Ruiz-Palacios P, Díaz-Greene EJ, Rodríguez-Weber FL

Language: Spanish
References: 15
Page: 457-466
PDF size: 521.55 Kb.

ABSTRACT

Background: Most severe cases of metabolic acidosis are caused by lactic acid or ketones (diabetic ketoacidosis), and to a lesser extent by methanol, ethylene glycol, salicylates, and drugs such as metformin.
Clinical cases: This paper reports two clinical cases (a 70-year-old woman and a 63-year-old man) with lactic acidosis by metformin.
Conclusions: Lactic acidosis by metformin is a complication of treatment in diabetic patients, highlighting the importance of replacement therapy as a treatment and that of an early diagnosis.

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