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Colegio de Medicina Interna de México.

2022, Number 2

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Med Int Mex 2022; 38 (2)

Hypouricemia: a forgotten entity

Sánchez-Pérez H, Carrillo-Esper R, Zavala-González MÁ, Carrillo-Córdova DM

Language: Spanish
References: 25
Page: 388-396
PDF size: 480.12 Kb.


ABSTRACT

Hypouricemia is a biochemical disorder and marker for primary or secondary tubulophaty and other underlying illnesses, defined as a serum uric acid concentration lesser than 2 mg/dL. It occurs in approximately 2% of hospitalized patients and in lesser than 0.5% of general population. Hypouricemia may be caused by decreased uric acid production, uric acid oxidation or decreased renal tubular reabsortion. Differential diagnosis of hypouricemia is usually made by evaluating the fractional excretion of uric acid. Patients with hypouricemia may have an increased incidence of acute kidney injury related to exercise and reduced kidney function. The aim of this paper is to review current concepts related to hypouricemia and emphasize the importance of its evaluation and follow-up.


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