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Coordinación General de Investigación de la Facultad de Salud Pública y Nutrición y la Dirección General de Sistemas e Informática de la Universidad Autónoma de Nuevo León

2022, Number 2

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Rev Salud Publica Nutr 2022; 21 (2)

Bromelain and its therapeutic applications in the human gastrointestinal system: a scoping review

González TM, Valencia RKI, Martínez BAZ, Márquez ZL, Ramírez LE

Language: Spanish
References: 44
Page: 39-49
PDF size: 549.22 Kb.


ABSTRACT

Introduction: Bromelain has been used for therapeutic purposes since the 19th century. Different studies have been reported both in vitro experimentation and in animals and even in humans that showed favorable results for the gastrointestinal system. Objective: To develop a review of the investigations carried out in the last two decades that refer to the gastrointestinal therapeutic use of bromelain in humans, animals and in vitro experimentation. Material and method: An exploratory review (scoping review) was carried out based on the PRISMA requirements for this type of review. The documentary search was carried out in the studies published in the PubMed, ScienceDirect, Scopus, Google Scholar, Springer Link and Wiley databases. Results: Thirteen articles were found, five clinical trials, four in animals and four in vitro. The results of the therapeutic effects of bromelain were significant due to its properties as an analgesic, antacid, anticancer, antiinflammatory, immunomodulatory, prebiotic, probiotic, in reducing constipation and gastric emptying. Conclusions: Bromelain has beneficial effects at the gastrointestinal level in humans, it is only necessary to deepen the evidence to continue the research of the last two decades.


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