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ISSN 1028-4818 (Electronic)

2021, Number 2

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Mul Med 2021; 25 (2)

Role of the microbiological studies in pancreatic necrosis

Turruelles RA, Ricardo MD, Pérez SM, Sánchez BEC, Sánchez VR

Language: Spanish
References: 14
Page:
PDF size: 446.11 Kb.


ABSTRACT

Introduction: infection of pancreatic necrosis is the most serious local complication of acute pancreatitis. It occurs in approximately 35% of patients and has a mortality rate close to 80%.
Objective: to identify the microbiological spectrum of infected pancreatic necrosis
Methods: we carried out a longitudinal, descriptive, prospective study in the intensive care unit of the Carlos Manuel de Céspedes University Hospital in the city of Bayamo, Cuba, in the period from January 2012 to December 2018. 71 patients with the diagnosis or suspicion of infected acute necrotizing pancreatitis that required necrosectomy with intraoperative culture taking.
Results: of the total number of patients in the series, the majority were male, representing 56.3% of the sample. the most frequently found etiology was lithiasis with 38 patients (53.5%). While 52 patients (73.2%) had more than 50% of the pancreatic gland with necrosis. In 63 patients, the presence of necrosis infection was confirmed. With a predominance of monomicrobial infection in 48 cases (76.2%). The most frequent germ found was E. coli (47.9%). Post-operative mortality was 15 patients (21.1%). Of them 14 patients (93.3%) with infection after necrosectomy.
Conclusions: monomicrobial infection by E. coli predominated. Patients with confirmed bacterial growth post necrosectomy had higher mortality.


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