2022, Number 1
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Dermatología Cosmética, Médica y Quirúrgica 2022; 20 (1)
Multiple clear cell acanthoma: A case report and review
Guarda TR, Ñanco MCA, Castro MAI, Sanz AA, Hasbún AP
Language: Spanish
References: 60
Page: 37-43
PDF size: 645.86 Kb.
ABSTRACT
Clear cell acanthoma (CCA) in its multiple form of presentation
is highly infrequent. We here describe a Chilean patient with
multiple lesions of CCA, the eight case reported by Iberoamerican
authors in the available international literature. A 70-yearold
male consulted for bilateral multiple erythematous mostly
asymptomatic papules on his thighs and legs that had progressively
appeared throughout 30 years. Histological examination
of two papules confirmed the diagnosis of CCA. He was successfully
treated with cryosurgery. An extensive review of the
literature allowed us to find 54 reported cases of multiple CCA
and to summarize its main epidemiologic, clinical, dermoscopic,
histologic and therapeutic findings. The diagnosis of multiple
CCA must be suspected in a patient with gradual appearance
of multiple red-brownish papules throughout years mainly on
the lower limbs. Although the typical clinical and dermoscopic
findings point to the diagnosis, this must be confirmed by a
histologic study of an entire papule.
REFERENCES
Degos R, Delort J, Civatte J y Poiares Baptista A, Epidermal tumor with an unusual appearance: clear cell acanthoma, Ann Dermatol Syphiligr (París) 1962; 89:361-71.
Desmons F, Breuillard F, Thomas P, Leonardelli J e Hildebrand HF, Multiple clear-cell acanthoma (Degos): histochemical and ultrastructural study of two cases, Int J Dermatol 1977; 16(3):203-13.
Kerl H, Clear-cell acanthoma, Hautarzt 1977; 28(9):456-62.
Degos R y Civatte J, Clear cell acanthoma: experience of 8 years, Br J Dermatol 1970; 83:248-54.
Tempark T, Shwayder T, Clear cell acanthoma, Clin Exp Dermatol 2012; 37(8):831-7.
Benedetto CJ y Athalye L, Clear cell acanthoma, StatPearls 2020.
Witkowski J y Parish L, Clear cell acanthoma, Int J Dermatol 1979; 18:162-3.
Naeyaert JM, De Bersaques J, Geerts ML y Kint A, Multiple clear cell acanthomas: a clinical, histological and ultrastructural report, Arch Dermatol 1987; 123:1670-3.
García-Gavín J, González-Vilas D, Montero I, Rodríguez-Pazos L, Pereiro MM y Toribio J, Disseminated eruptive clear cell acanthoma with spontaneous regression: further evidence of an inflammatory origin?, The American Journal of Dermatopathology 2011; 33(6):599-602.
Jacyk WK, Baran W y Essop A, Multiple pigmented clear cell acanthoma in an African patient, J Eur Acad Dermatol Venereol 2016; 30(3): 494-6.
González-Guerra E, Rodríguez JR, Casado AF, Taboada AC, Toro JAC y Bran EL, Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids, Anais Bras Dermatol 2017; 92:27-9.
Finch TM y Tan CY, Clear cell acanthoma developing on a psoriatic plaque: further evidence of an inflammatory aetiology?, Br J Dermatol 2000; 142(4):842-4.
Ohnishi T y Watanabe S, Immunohistochemical characterization of keratin expression in clear cell acanthoma, Br J Dermatol 1995; 133(2):186-93.
Thorne E y Fusaro R, Multiple clear cell acanthomas in a patient with lamellar ichthyosis, Dermatologica 1971; 143:105-10.
Landry M y Winkclmann R, Multiple clear cell acanthoma and ichthyosis, Arch Dermalol 1971; 105:171-83.
Hatakeyama M, Oka M, Fukunaga A, Kunisada M, Funasaka Y y Nishigori C, A case of multiple facial clear cell acanthomas successfully treated by cryotherapy, Indian J Dermatol 2013; 58:162.
Zhou S, Qiao J, Bai J, Wu Y, Jiang X, Pan Y et al., Multiple eruptive clear cell acanthoma, Indian J Dermatol 2018; 63(2):190-2.
Kim CY, Kim NG y Oh CW, Multiple reddish weeping nodules on the genital area of a girl, Clin Exp Dermatol 2010; 35:67-9.
Délacrétaz J, Acanthomes à cellules claires, Dermatologica 1964; 129:147-53.
Martínez Escanamé M, Arzberger E, Hofmann-Wellenhof R y Massone C, Multiple clear-cell acanthomas, Australas J Dermatol 2015; 56:46-8.
Bordas X, Vives P, Martí R, Palou J, Llagostera M y Mascaró JM, Multiple clear-cell acanthoma, Med Cutan Ibero Lat Am 1984; 12:457-60.
Morillo V, Manrique P, Zabalza I y Artola JL, Eruptive clear cell acanthoma, Actas Dermosifiliogr 2009; 100: 244-6.
De Miguel R, Disseminated eruptive clear cell acanthoma: a case report for treatment, J Am Acad Dermatol 2012; 66 (4):ab49.
García Almagro D, Bueno C, Corripio F, Lecona M et al., Acantoma de células claras múltiple en una paciente con psoriasis tratada con 5-fluoruracilo, Med Cutan Ibero Lat Am 1979; 7:109-113.
Trau H, Fisher B y Schcwach-Millet M, Multiple clear cell acanthomas, Arch Dermatol 1980; 116:433-4.
Su O, Dizman D, Onsun N, Ozkaya D, Tosuner Z, Bahali A et al., Multiple giant clear cell acanthomas, Indian J Dermatol Venereol Leprol 2016; 82:218.
Innocenzi D, Barduagni F, Cerio R y Wolter M, Disseminated eruptive clear cell acanthoma-a case report with review of the literature, Clin Exp Dermatol 1994; 19:249-53.
Burg G, Würsch T, Fäh J y Elsner P, Eruptive hamartomatous clear-cell acanthomas, Dermatology 1994; 189:437-9.
Stembridge N, Rytina E y Norris P, Dermpath Clinic: multiple clear cell acanthomas, Eur J Dermatol 2017; 27:566-7.
Fandrey K, Rabenhorst S, Fedler R y Frosch PJ, Multiple Klarzellakanthome, Hautarzt 1995; 46(12):865-8.
Monari P, Farisoglio C, Gualdi G, Botali G, Ungari M y Calzavara-Pinton P, Multiple eruptive clear cell acanthoma, J Dermatol 2010; 2:25-7.
Rotaru M, Iancu GM, Gheuca˘ Solova˘stru L, Glaja RF, Grosu F, Bold A et al., A rare case of multiple clear cell acanthoma with a relatively rapid development of the lower legs, Rom J Morphol Embryol 2014; 55:1171-9.
Tiodorovic-Zivkovic D, Lallas A, Longo C, Moscarella E, Zalaudek I y Argenziano G, Dermoscopy of clear cell acanthoma, J Am Acad Dermatol 2015; 72:s47-9.
Kavanagh GM, Marshman G y Burton JL, Multiple clear cell acanthomas treated by cryotherapy, Australas J Dermatol 1995; 36(1):33-4.
Kneitz H, Bröcker EB y Ugurel S, Langsam wachsende Knoten an beiden Unterschenkeln eines 54-jährigen Patienten, J Deutsch Dermatol Gesellschaft 2009; 7(1):63-5.
Potenziani S, Applebaum D, Krishnan B, Gutiérrez C y Diwan AH, Multiple clear cell acanthomas and a sebaceous lymphadenoma presenting in a patient with Cowden syndrome: a case report: cs patient with multiple ccas and an sla, J Cutan Pathol 2017; 44(1):79-82.
Somlai B, Daróczy J y Rutkai K, Multiple clear cell acanthomas, Z Hautkr 1988; 63:230-3.
Bonnetblanc JM, Multiple clear cell acanthoma, Arch Dermatol 1981; 117(1):1.
Donati P, Leonetti F y Palamara G, Due casi di acantoma a cellule chiare múltiplo, Dermatologia Oggi 1991; 5:29-31.
Balus L, Cainelli T, Cristiani R y Donati P, Acanthome à cellules claires multiple et familial, Ann Dermatol Venereol 1984; 111:665-6.
Ebner H, Multiple Klarzellakanthome, Z Hautkr 1974; 49:541-6.
Williams rea, Lever R, Seywright M, Multiple clear cell acanthomas: treatment by cryotherapy, Clin Exp Dermatol 1989; 14:300-1.
Betti R, Bruscagin C, Inselvini E, Palvarini M y Crosti C, Successful cryotherapic treatment and overview of multiple clear cell acanthomas, Dermatol Surg 1995; 21(4):342-4.
Bang R, Multiple clear cell acanthomas in association with hepatitis c: a novel presentation, J Am Acad Dermatol 2010; 62(3):ab39.
Shirai A, Saeki H, Matsuzaki H, Ito K y Nakagawa H, Multiple clear cell acanthoma associated with multiple Bowen’s disease, Int J Dermatol 2014; 53(8):e386-8.
Blum A, Metzler G, Bauer J, Rassner G y Garbe C, The dermatoscopic pattern of clear-cell acanthoma resembles psoriasis vulgaris, Dermatology 2001; 203(1):50-2.
Lacarrubba F, De Pasquale R y Micali G, Videodermatoscopy improves the clinical diagnostic accuracy of multiple clear cell acanthoma, Eur J Dermatol 2003; 13(6):596-8.
Bugatti L, Filosa G, Broganelli P y Tomasini C, Psoriasis-like dermoscopic pattern of clear cell acanthoma, J Eur Acad Dermatol Venereol 2003; 17(4):452-5.
Zalaudek I, Hofmann-Wellenhof R y Argenziano G, Dermoscopy of clear-cell acanthoma differs from dermoscopy of psoriasis, Dermatology 2003; 207(4):428.
Akin FY, Ertam I, Ceylan C, Kazandi A y Ozdemir F, Clear cell acanthoma: new observations on dermatoscopy, Indian J Dermatol Venereol Leprol 2008; 74(3):285.
Ardigo M, Buffon RB, Scope A, Cota C, Buccini P, Berardesca E et al., Comparing in vivo reflectance confocal microscopy, dermoscopy and histology of clear-cell acanthoma, Dermatol Surg 2009; 35:952-9.
Goette D y Diakon C, Multiple clear cell acanthomas, Arch Dermatol 1983; 119:359-61.
Baden T, Woodley D y Wheeler C, Multiple clear cell acanthomas, J Am Acad Dermatol 1987; 16:1075-8.
Fernández-Obregón AC, Residents’ corner: cryosurgery of clear cell acanthoma, J Dermatol Surg Oncol 1986; 12(7):689-92.
Altman AR, Basler E y Rosen T, Cryosurgical treatment of clear cell acanthoma, Int J Dermatol 1989; 28(5):334-5.
Duperrat B y Mascaró JM, L’acanthome à cellules claires, Ann Derm Syph 1965; 92:5-23.
Délacrétaz J, Christeller A, Loi-Zedda P y Lenggenhager R, Acanthome à cellules claires, Dermatologica 1967; 135:304.
Kaufmann J, Eichmann A, Meves C et al., Klarzellakanthom (multiple): demonstrationen. Dermatologica 1976; 153:116-7.
Varotti C, Passarini B y Baratta L, Acantoma a cellule chiare multiplo. Studio istoiogico et ultrastrutturale di un caso, G Ital Dermatol Venereol 1979; 144:765-70.
Dupré A y Viraben R, Forme eruptive de l’acanthome à cellules claires, Nouv Dermatol 1987; 6:485.