2022, Number 04
<< Back Next >>
Ginecol Obstet Mex 2022; 90 (04)
Extreme maternal morbidity (near miss) for severe dengue. A case report
Escalante-Rosique JR, Tejeda-Mollinedo W, García-Hernández GG, Betanzos-Ramírez F, Martínez-Hernández CM
Language: Spanish
References: 16
Page: 364-370
PDF size: 349.37 Kb.
ABSTRACT
Background: Dengue is caused by a virus belonging to the Flaviviridae family,
there are four related serotypes: DENV-1, DENV-2, DENV-3, DENV-4 transmitted by
the bite of the female mosquito of the species Aedes aegypti and Aedes albopictus.
Clinical case: 19-year-old female patient, 36 weeks pregnant by date of last
menstrual period and diagnosed with dengue due to positive serology (Ag-NS1) and
thrombocytopenia (68,000/mm3). The illness started with fever of 38.0°C, of three days
of evolution accompanied by arthralgias, myalgias, retro ocular pain and uterine contractions.
The patient was admitted to the intensive care unit due to respiratory failure
(which required invasive mechanical ventilation), acute renal and hematologic failure,
following cesarean section. She required surgical reintervention for intra-abdominal
bleeding due to coagulation disorders. During her hospital stay she required 50 platelet
concentrates, 8 erythrocyte concentrates, 14 fresh plasmas and 4 platelet apheresis.
After 14 days of hospital stay he was discharged due to clinical improvement.
Conclusion: If no immediate action is taken, severe dengue is a cause of fatal
mother-child outcome. The timely identification of the complications associated
with this disease in pregnant women highlights the importance of prevention, early
diagnosis and treatment. Similarly, it is important that in pregnant patients with this
comorbidity, the obstetrics service should intervene in a timely manner in pre- and
post-surgical surveillance.
REFERENCES
Vázquez-Pichardo M, Rosales-Jiménez C, Núñez-León A, Rivera-Osorio P, et al. Serotipos de dengue en México durante 2009 y 2010. Bol Med Hosp Infant Mex 2011; 68 (2): 103-10. http://www.scielo.org.mx/scielo.php?pid=S1665- 11462011000200005&script=sci_arttext
Rodríguez-Martínez LM, Izquierdo-Aquino F, González- Fernández MI, Correa-Morales F, et al. Distribución de Aedes albopictus (Skuse 1895) en Tabasco, México durante 2015-2018. Horiz Sanitario 2019; 18 (2): 159-65. https:// doi.org/10.19136/hs.a18n2.2689.
México: Secretaría de Salud, CENETEC. Clasificación, diagnóstico y tratamiento integral del dengue. Resumen de evidencias y recomendaciones: Guía de Práctica Clínica. 2016. http://www.cenetec.salud.gob.mx/contenidos/gpc/ catalogoMaestroGPC.html
Luengas LL, Tyga DC, Herrera VM, Villar-Centeno LA. Caracterización del estado de salud de las personas en su periodo de convalecencia de un episodio de dengue. Biomédica 2015; 36 (2): 89-97. https://doi.org/10.7705/ biomedica.v36i0.3019
Galindo-Mateu N, Roig-Casabán N, Moreno-Collado A, Gurrea-Soteras M, et al. Near-miss o casi pérdida en un hospital de referencia. Progresos Obstet y Ginecol 2010; 53 (10): 399-402. doi: 10.1016/j.pog.2010.07.002
Franco-Yáñez DE, Hernández-Pacheco JA. Monitoreo de morbilidad materna extrema (near miss) como compromiso internacional para complementar la calidad de la atención en salud materna. Perinatol y Reprod Humana 2016; 30 (1): 31-38. https://doi.org/10.1016/j.rprh.2016.03.004
Anders KL, Nguyet NM, Chau NVV, Hung NT, et al. Epidemiological Factors Associated with Dengue Shock Syndrome and Mortality in Hospitalized Dengue Patients in Ho Chi Minh City, Vietnam. Am J Trop Med Hyg 2011; 84 (1): 127- 34. doi:10.4269/ajtmh.2011.10-0476
Hung NT, Lan NT, Lei H, Lin Y, et al. Association between sex, nutritional status, severity of dengue hemorrhagic fever, and immune status in infants with dengue hemorrhagic fever. Am J Trop Med Hyg 2005; 72 (4): 370-4. http:// citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.514 .6126&rep=rep1&type=pdf
Lapphra K, Sangcharaswichai A, Chokephaibulkit K, Tiengrim S, et al. Evaluation of an NS1 antigen detection for diagnosis of acute dengue infection in patients with acute febrile illness. Diagn Microbiol Infect Dis 2008; 60 (4): 387- 91. doi:10.1016/j.diagmicrobio.2007.11.010
Romero-Machado C, Stankiewicz-Machado E, Rohloff RD, Azevedo M, et al. Is Pregnancy Associated with Severe Dengue? A Review of Data from the Rio de Janeiro Surveillance Information System. PLoS Negl Trop Dis 2013; 7 (5): 2-6. doi: 10.1371/journal.pntd.0002217
Gehlot H, Yadav OP, Sharma S, Nagar GG, et al. A study of dengue fever in pregnancy and its maternal and fetal prognosis. Int J Reprod Contracept Obstet Gynecol 2017; 6 (8): 3414- 7. http://dx.doi.org/10.18203/2320-1770.ijrcog20173454
World Health Organization. (2009). Dengue guidelines for diagnosis, treatment, prevention and control: new edition. World Health Organization. https://apps.who.int/iris/ handle/10665/44188
Paixão ES, Campbell OM, Teixeira MG, Costa MCN, et al. Dengue during pregnancy and live birth outcomes: a cohort of linked data from Brazil. BMJ 2019; 9 (7): 1-8. doi:10.1136/bmjopen-2018-023529
Paixão ES, Costa MC, Texeira MG, Harron K, et al. Symptomatic dengue infection during pregnancy and the risk of stillbirth in Brazil, 2006-12 : a matched case-control study. Lancet Infect Dis 2017; 17 (9): 957-64. doi: 10.1016/S1473- 3099(17)30366-3
Say L, Pattinson RC, Gülmezoglu AM. WHO systematic review of maternal morbidity and mortality: the prevalence of severe acute maternal morbidity (near miss). Reprod Health 2004; 1: 3. doi: 10.1186/1742-4755-1-3
Jiménez-Ibáñez LC, Hernández-Pérez SY, García-Padrón OA. Fiebre hemorrágica por dengue durante el embarazo. Reporte de un caso. Ginecol Obstet Méx 2019; 87 (4): 257- 61. https://doi.org/10.24245/gom.v87i4.2510