2022, Number 1
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salud publica mex 2022; 64 (1)
Liver cancer mortality in Mexico: trend analysis from 1998 to 2018
Álvarez CS, Espinosa-Tamez P, López-Ridaura R, Lamadrid-Figueroa H, Melchor-Ruan J, McGlynn KA, Lajous M
Language: English
References: 31
Page: 14-25
PDF size: 569.46 Kb.
ABSTRACT
Objective. To examine overall, sex, and state-specific liver
cancer mortality trends in Mexico.
Materials and methods.
Joinpoint regression was used to examine the trends
in age-standardized mortality rates of liver cancer between
1998-2018. Estimated annual percent change with 95% confidence
intervals (95%CI) were computed. Age-period-cohort
models were used to assess the effects of age, calendar year,
and birth cohort.
Results. The state-specific mortality rates
ranged from 3.34 (Aguascalientes) to 7.96 (Chiapas) per
100 000 person-years. Sex-specific rates were roughly equal,
nationwide. Overall, we observed a statistically significant
decrease in liver cancer mortality rates between 1998-2018
(annual percent change, -0.8%; 95%CI -1.0, -0.6). The overall
age-period-cohort models suggest that birth cohort may be
the most important factor driving the trends.
Conclusions. While there was overall decline in liver cancer mortality,
differences in rates by region were observed. The regional
differences may inform future studies of liver cancer etiology
across the country.
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