2021, Number 1
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MEDICC Review 2021; 23 (1)
Can Anti-Ribosomal Antibodies Improve Systemic Lupus Erythematosus Diagnosis?
Kokuina E
Language: English
References: 10
Page: 90-91
PDF size: 118.72 Kb.
Text Extraction
Systemic lupus erythematosus (SLE) is an autoimmune disease
of unknown etiology. The only means of reducing its morbidity and
mortality remains early diagnosis followed by timely medical treatment.
SLE affects all populations worldwide, although prevalence
rates differ between population groups, with higher rates among
women of reproductive age and for African, Asian, and Hispanic
ethnicities.
The possibility of SLE diagnosis should be kept in mind during
daily medical practice, not because of its high frequency, but
because of the pronounced heterogenicity of its clinical presentation;
of all autoimmune diseases, SLE probably has the greatest
diversity in clinical manifestations. Biomarkers that can diagnose
and differentiate SLE from other rheumatic autoimmune diseases
are needed. However, in more than 50 years of research, no
single biomarker has emerged capable of identifying SLE in diagnostic
tests.
REFERENCES
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Kokuina E, Chico Capote A, Estevez del Toro M, Tamargo Barbeito T, Milian Olivares, Sanchez Bruzon Y. (2020), Anticuerpos anti-proteína P ribosomal: utilidad diagnóstica en el lupus eritematoso sistémico y asociación con nefritis lúpica, Original Research. [Unpublished study]. Spanish.