2020, Number 4
Usefulness of betamethasone in the prevention of postoperative pain in lumbar disc herniation
Language: Spanish
References: 19
Page: 721-734
PDF size: 467.20 Kb.
ABSTRACT
Introduction: use of corticosteroids is an effective strategy to reduce postoperative pain.Objective: to determine usefulness of betamethasone in the prevention of postoperative pain in patients operated for lumbar disc herniation.
Methods: a quasi-experimental study was carried out in 100 patients operated for lumbar disc herniation at «Arnaldo Milián Castro» Clinico-Surgical University Hospital, in Villa Clara province from April 2013 to December 2015. They were divided into a control group and a study one; prior to surgical incision, intravenous diclofenac 75mg and betamethasone 8mg were administered (only in the study group).
Results: 70% of the patients were male, and the mean age was 45.99 years. In the study group, the time of onset of pain (X2 = 52,217, p < 0,000) and its intensity, at 4, 8 and 24 hours, was significantly lower than in the control group (pα <0.010, pα <0.001 and p < 0.001); 48% of the patients were able to get up without pain, 32 % less required rescue analgesia, and the degree of satisfaction was significantly better.
Conclusions: administration of betamethasone before surgical incision was very useful in the prevention of postoperative pain in patients operated for lumbar disc herniation.
REFERENCES
Vasallo Comendeiro VJ, Arjona Fonseca S. Analgesia multimodal postoperatoria en cirugía ginecológica y obstétrica urgente. Rev Cubana Anestesiol Reanim [internet]. dic. 2011 [citado 14 sep. 2017];10(3):[aprox. 8 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1726-67182011000300005
Cosamalón-Gan I, Cosamalón-Gan T, Mattos-Piaggio G, Villar-Suárez V, García-Cosamalón J, Vega-Álvarez JA. Inflammation in the intervertebral disc herniation. Neurocirugía (Astur) [internet]. 2020 Mar. 10 [citado 13 mayo 2020];(20):[aprox. 344 p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32169419/
Kyoung-Tae K, Dae-Chul C, Joo-Kyung S, Young-Baeg K, Hyun K, Kwang-Sup S, et al. Intraoperative systemic infusion of lidocaine reduces postoperative pain after lumbar surgery: a double-blinded, randomized, placebo-controlled clinical trial. Spine J [internet]. 2014 Aug. 1 [citado 5 oct. 2018];14(8):[aprox. 8 p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/24216403/ 9. Miller R, Cohen N, Eriksson L, Fleisher L, Wiener-Kronish J, Young W. Miller´s Anesthesia. 8th ed. Philadelphia: Churchill Livingstone/Elsevier; 2016.
Frizziero A, Causero A, Bernasconi S, Papalia R, Longo M, Sessa V, et al. Efficacy of betamethasone valerate medicated plaster on painful chronic elbow tendinopathy: a double-blind, randomized, placebo-controlled trial. Muscles Ligaments Tendons J [internet]. 2016 May 19 [citado 5 oct. 2018];6(1):[aprox. 9 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915452/
Kim YJ, Lee GY, Kim DY, Kim CH, Baik HJ, Heo S. Dexamathasone added to levobupivacaine improves postoperative analgesia in ultrasound guided interscalene brachial plexus blockade for arthroscopic shoulder surgery. Korean J Anesthesiol [internet]. 2012 [citado 14 sep. 2017];62(2):[aprox. 5 p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/22379567/
De Oliveira GS, Almeida MD, Benzon HT, McCarthy RJ. Perioperative single dose systemic dexamethasone for postoperative pain: a meta-analysis of randomized controlled trials. Anesthesiology [internet]. 2011 [citado 14 sep. 2017];115(3):[aprox. 14 p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/21799397/
Segelman J, Pettersson HJ, Svensén C, Divander MB, Barenius B, Segelman J. Analgesic effect of a single dose of betamethasone after ambulatory knee arthroscopy: a randomized controlled trial. J Anesth [internet]. 2016 Jul. 1 [citado 14 sep. 2017];30(5):[aprox. 8 p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/27370892/
Naghibi T, Dobakhti F, Mazloomzadeh S, Dabiri A, Molai B. Comparison between intrathecal and intravenous betamethasone for post-operative pain following cesarean section: a randomized clinical trial. Pak J Med Sci [internet]. 2013 [citado 14 sep. 2017];29(2):[aprox. 5 p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/24353567/