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ISSN 1405-1710 (Print)

2021, Number 3

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Rev Cent Dermatol Pascua 2021; 30 (3)

Pyoderma gangrenosum associated with rheumatoid arthritis

Trejo-Acuña JR, Medina-Bojórquez A, Ramos-Garibay JA, Zárate-Flores LM, Santos-Ortíz MF

Language: Spanish
References: 13
Page: 148-155
PDF size: 509.36 Kb.


ABSTRACT

Pyoderma gangrenosum is an inflammatory dermatosis that is part of neutrophilic dermatoses, in more than half of the cases it has been associated with some systemic disease. We present the case of a 52-year-old man with disseminated dermatosis to the anterior and posterior trunk, the lower third of the upper limbs and the lower third of the lower limbs is reported. The dermatosis consisted of numerous ulcers of various shapes, some of them larger than 10 cm in diameter, with a clean bottom, undercut edges and purplish erythematous. Histopathological findings were consistent with pyoderma gangrenosum. The clinical diagnosis of a disseminated ulcer variety associated with rheumatoid arthritis was established.


REFERENCES

  1. Maverakis E, Marzano AV, Le ST, Callen JP, Brüggen MC, Guenova E et al. Pyoderma gangrenosum. Nat Rev Dis Primers. 2020; 6: 81.

  2. Kridin K, Damiani G, Cohen AD. Rheumatoid arthritis and pyoderma gangrenosum: a population-based case-control study. Clin Rheumatol. 2021; 40: 521-528.

  3. Acosta J, Águila CR. Pioderma gangrenoso. Med Int Méx. 2014; 30: 92-98.

  4. Alavi A, French LE, Davis MD, Brassard A, Kirsner RS. Pyoderma gangrenosum: an update on pathophysiology, diagnosis and treatment. Am J Clin Dermatol. 2017; 18: 355-372.

  5. George C, Deroide F, Rustin M. Pyoderma gangrenosum - a guide to diagnosis and management. Clin Med (Lond). 2019; 19: 224-228.

  6. Leger M, Newlove T, Chu J, Meehan S, Stein J. Pustular pyoderma gangrenosum. Dermatol Online J. 2011; 17: 17.

  7. Milam EC, Brinster NK. Superficial granulomatous pyoderma of the leg improved after conservative management with Unna boot and intralesional steroid injections. JAAD Case Rep. 2018; 4: 797-799.

  8. Vences CM, Malo JR, Navarrete FG. Pioderma gangrenoso ulcerado diseminado: comunicación de un caso. Dermatología Rev Mex. 2009; 53: 96-99.

  9. Sawka E, Zhou A, Latour E, Friedman M, Ortega-Loayza AG. Inflammatory arthritis-associated pyoderma gangrenosum: a systematic review. Clin Rheumatol. 2021; 40: 3963-3969.

  10. Kridin K, Cohen AD, Amber KT. Underlying systemic diseases in pyoderma gangrenosum: a systematic review and meta-analysis. Am J Clin Dermatol. 2018; 19: 479-487.

  11. Ashchyan HJ, Butler DC, Nelson CA, Noe MH, Tsiaras WG, Lockwood SJ et al. The association of age with clinical presentation and comorbidities of pyoderma gangrenosum. JAMA Dermatol. 2018; 154: 409-413.

  12. Callen JP, Jackson JM. Pyoderma gangrenosum: an update. Rheum Dis Clin North Am. 2007; 33: 787-802.

  13. Borda LJ, Wong LL, Marzano AV, Ortega-Loayza AG. Extracutaneous involvement of pyoderma gangrenosum. Arch Dermatol Res. 2019; 311: 425-434.




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