2021, Number 1
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VacciMonitor 2021; 30 (1)
Clinical and epidemiology characterization of intussusception at the Centro Habana Paediatric Hospital before rotavirus vaccine introduction
Gámez-Fonts LN, Ramírez-Guirado A, González-Aquino Y, Avila-Ochoa I, Luis-Gonzálvez IP, Amin-Blanco N, Linares-Pérez N, Peón-Valdés TA
Language: Spanish
References: 23
Page: 33-38
PDF size: 406.27 Kb.
ABSTRACT
The knowledge of the baseline incidence rates of intussusception among infants in Cuba are necessary to introduce the rotavirus vaccine into the Cuban immunization schedule. With the aim of characterizing the clinical presentation and epidemiology of intussusception a surveillance study was performed in children less than 1 years old with intussusception, in the pediatric surgery service at the Centro Habana Pediatric Hospital in Havana city between November 2017 and April, 2018. This study is the precursor of an active sentinel hospital surveillance for intussusception in children under 1 year of age, as a part of the project Rotavirus vaccine promoted by Instituto Finlay de Vacunas. Data were collected for each notified case by surgeons using a brief study questionnaire (Sentinel surveillance file for intussusception). A total of nine patients were diagnosed with intussusception, most cases presented at 5 months of age (44.4%), and all cases were confirmed by abdominal ultrasonography. The incidence of intussusception was 1.41%. The most frequent symptoms were rectal bleeding (77.8%), irritability (66.7%) and vomiting (55.6%). Intussusceptions reduction by non-surgical methods was used in eight cases, mainly air enema (62.5%). These results are now available to build the body of scientific evidence for baseline rates of intussusception in children less than 1 year of age, prior to the introduction of the rotavirus vaccine in Cuba.
REFERENCES
Burke RM, Tate JE, Kirkwood CD. Steele AD, Parashar UD. Current and new rotavirus vaccines. Curr Opin Infect Dis.2019;32(5):435-44. doi: https://10.1097/QCO.0000000000000572. (Consultado en línea: 28 de septiembre del 2019).]
World Health Organization. Rotavirus vaccines: WHO position paper-January 2013. Wkly Epidemiol Rec.2013;88(5):49-64.]
Center for Disease Control. Withdrawal of rotavirus vaccine recommendation. MMWR Morb Mortal Wkly Rep.1999;48(43):1007.]
Center for Disease Control. Prevention of rotavirus gastroenteritis among infants and children recommendations of the advisory committee on immunization practices (ACIP). MMWR Recomm Rep.2009;58(RR-2):1-25.]
Stowe J, Andrews N, Ladhani S, Miller E. The risk of intussusception following monovalent rotavirus vaccination in England: a self-controlled case-series evaluation. Vaccine.2016;34:3684-9. doi: https://10.1016/j.vaccine.2016.04.050.]
Patel MM, Lopez-Collada VR, Bulhoes MM, De Oliveira LH, Bautista Marquez A, Flannery B, et al. Intussusception risk and health benefits of rotavirus vaccination in Mexico and Brazil. N Engl J Med.2011;364:2283-92.]
Velazquez FR, Colindres RE, Grajales C, Hernández MT, Mercadillo MG, Torres FJ, et al. Postmarketing surveillance of intussusception following mass introduction of the attenuated human rotavirus vaccine in Mexico. Pediatr Infect Dis J.2012;31(7):736-44.]
Buttery JP, Danchin MH, Lee KJ, Carlin JB, McIntyre PB, Elliott EJ, et al. Intussusception following rotavirus vaccine administration: post-marketing surveillance in the national immunization program in Australia. Vaccine.2011;29:3061-6.]
WHO. Global Advisory Committee on Vaccine Safety, 6-7 December 2017. Wkly Epidemiol Rec.2018;93:17-32.]
World Health Organization. Acute intussusception in infants and children/Incidence, clinical presentation and management, a global perspective. Geneva: World Health Organization;2002.]
Yung CF, Chan SP, Soh S, Tan A, Thoon KC. Intussusception and monovalent rotavirus vaccination in Singapore: self-controlled case series and risk-benefit study. J Pediatr. 2015;167(1):163-8.e1. doi: https://10.1016/j.jpeds.2015.03.038]
World Health Organization. Generic protocols for (i) hospital-based surveillance to estimate the burden of rotavirus gastroenteritis in children and (ii) a community-based survey on utilization of health care services for gastroenteritis in children: field test version. Geneva: World Health Organization; 2002.]
Jiang J, Jiang B, Parashar U, Nguyen T, Bines J, Patel MM. Childhood intussusception: a literature review. PLoS One.2013;8(7):e68482. doi: https://10.1371/journal.pone.0068482]
Clark AD, Hasso-Agopsowicz M, Kraus MW, Stockdale LK, Sanderson CF B, Parasha UD, Tate JE. Update on the global epidemiology of intussusception: a systematic review of incidence rates, age distributions and case-fatality ratios among children aged <5 years, before the introduction of rotavirus vaccination. Int J Epidemiol.2019;48(4):1316-26. doi:https://10.1093/ije/dyz028 (Consultado en línea: 20 de Julio del 2019).]
Quevedo-Guanche L. Invaginación intestinal: clasificación, diagnóstico y tratamiento. Rev Cubana Cir.2007;46(4).Disponible en: http://scielo.sld.cu/scielo/php?script=sci_arttext&pid=S0034-74932007000400013.]
Vázquez-Merayo E, Anido-Escobar V, Vázquez-Martínez YE, Vázquez-Martínez YT. Invaginación intestinal en el niño, respuesta al tratamiento médico. Rev Cubana Pediatr.2015;87(3):265-72. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75312015000300002]
Armenteros-García A, Pascual-Héctor AM, Alfonso-Chang Y, Ballate-Machado D, Esquivel-Sosa L, Camacho-Hernández O, Gómez-Vera I. Reducción hidrostática en niños con invaginación intestinal. Medicen Electrón.2017;21(3):218-26. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30432017000300005&lng=es]
Hernández-Moore E. Invaginación intestinal. En: Colectivo de autores, editor. Pediatría Diagnóstico y tratamiento. La Habana: Editorial Ciencias Médicas;2016.p.570-2.]
Linares-Pérez Nivaldo. Introducción de la vacunación antineumocócica, un proyecto conjunto de la Biotecnología y el Sistema de Salud Cubano. Rev Cubana Pediatr.2017;89(Sup1):1-3. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75312017000500001&lng=es.]
Liu N, Yen C, Huang T, Cui P, Tate JE, Jiang B, et al. Incidence and epidemiology of intussusception among children under 2?years of age in Chenzhou and Kaifeng, China, 2009-2013. Vaccine.2018;36(51):7862-7. doi: https://10.1016/j.vaccine.2018.02.032.]
Restivo V, Costantino C, Tramuto F, Vitale F. Hospitalization rates for intussusception in children aged 0-59 months from 2009 to 2014 in Italy. Hum Vaccin Immunother.2017;13(2):445-9. doi: https://10.1080/21645515.2017.1264784.]
Latipov R, Khudoyorov R, Flem E. Childhood intussusception in Uzbekistan: analysis of retrospective surveillance data. BMC Pediatr.2011;11:22. doi: https://10.1186/1471-2431-11-22.]
Gluckman S, Karpelowsky J, Webster AC, McGee RG. Management for intussusception in children. Cochrane Database Syst Rev.2017;6(6):CD006476. doi: https://10.1002/14651858.CD006476.pub3.