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Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2021, Number 1

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Bol Clin Hosp Infant Edo Son 2021; 38 (1)

Congenital co-infection by Treponema pallidum and cytomegalovirus A neonatal case report

Yalaupari-Mejia JP, Arrellano-Galindo J, Mancilla-Ramírez J,González-Arenas E, Huerta-Romano JF, Reyes-Gómez U, Reyes-Hernández KL, Pila-Aranda G, Reyes-Hernández MU, Alonso-Pérez NC, Quero-Hernández A, Santiago-Valdivieso U, Marcos-Cabrera L

Language: Spanish
References: 22
Page: 65-69
PDF size: 185.06 Kb.


ABSTRACT

Congenital syphilis (CS) is a disease transmitted by Treponema pallidum to the fetus by transplacental circulation, usually from the 20th week of gestation. In 2019, Mexico reported 372 cases, on the other hand, infection by Congenital Cytomegalovirus (cCMV) is not considered mandatory notification. We report the first neonatal case of Coinfection by T. pallidum and CMV according to the medical literature in spanish and english. The clinical case is a premature newborn born in the Hospital de la Mujer in Mexico City, pregnancy 1, 21-year-mother without prenatal control, female product is obtained vaginally, weight 1570 g (‹PC 10); size 39 cm (‹PC 3), cefalic perimeter 27 cm (‹PC 3), thoracic perimeter 26 cm, braquial perimeter 26.5 cm, Apgar score of 6/7 at 1 and 5 minutes of life, it was classified as Capurro of 34 weeks of gestation, and intrauterine growth retardation (IUGR). The physical examination documented hepatosplenomegaly, within the study protocol the directed TORCH approach was considered. Treponemal tests were positive in both the mother and the neonate. The test for CC was positive in saliva. X-rays of long bones showed osteitis and epichondritis, it is managed with penicillin and ganciclovir. Prenatal control is important as a preventive way to diagnose syphilis in the mother and give early treatment to the case. Hepatomegaly in the newborn is an important clinical finding for the specific diagnostic approach.


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