2020, Number 4
Zinc deficiency in childbearing-aged women, Havana, Cuba
Language: Spanish
References: 38
Page: 1-19
PDF size: 734.55 Kb.
ABSTRACT
Introduction: Zinc deficiency is considered a global health problem. There is scarce information on zinc’s nutritional state in Cuban childbearing-aged women.Objective: Identify zinc and serum copper deficiency in childbearing-aged women, based on related factors, such as anemia, inflammation, excess weight and abdominal adiposity.
Methods: 104 seemingly healthy women from Havana, aged 18 to 40 were studied. A descriptive cross-sectional study was conducted. The determination of zinc, copper, hemoglobin, ferritin, C-reactive protein, alpha 1 glycoprotein, weight, size and minimum waist circumference was made, and the body mass index was calculated. International breakpoints were used for evaluation.
Results: The prevalence of iron deficiency, estimated by serum ferritin, zinc and serum copper was 66.3%(67/101), 36.2% (34/94) and 19.1% (18/94), respectively. Of women, 23.5% (24/102) had anemia, and 8.8% had inflammation (9/102) and 13% (13/100) estimated by CRP and AGP. Women with overweight 52.9% (54/102) and abdominal adiposity 61.8% (60/97) predominated.
Conclusions: The risk of zinc deficiency in the sample is high, the prevalence of decreased serum Zn exceeds 20%. There is no criterion for assessing the risk of copper deficiency as a public health problem. Zinc and copper deficiencies do not appear to be associated with anemia, inflammation and overall nutritional status. Additional tests are required to identify the magnitude of zinc and copper deficiencies and their possible causes.
REFERENCES
International Zinc Nutrition Consultative Group (IZiNCG). Assessment of the Risk of Zinc Deficiency in Populations and Options for Its Control. Technical Document # 1. FoodNutr Bull. 2004 [acceso 03/03/2013];25(1)(S2):S94-S203. Disponible en: http://www.izincg.org/publications/files/IZiNCGtechdocFNB2004.pdf]
Pita Rodríguez GM, Basabe Tuero B, Díaz Sánchez ME, Gómez Álvarez AM, Campos Hernández D, Arocha Oriol C, et al. Anaemia and Iron Deficiency Related to Inflammation, Helicobacter pylori Infection and Adiposityin Reproductive-age Cuban Women. Medicc Rev. 2017 [acceso 02/08/2017];19(2-3):10-17. Disponibleen:http://www.medicc.org/mediccreview/pdf.php?lang=en&id=584]
Raiten DJ, Sakr Ashour FA, Ross C, Meydani SN, Dawson HD, Stephensen CB, et al. Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE). J Nutr. 2015 [acceso 10/03/2016];145:1039S-108S. Disponible en: http://jn.nutrition.org/content/145/5/1039S.full.pdf+html?sid=f10550d8-c031-45e0-8676-e224adbe78257l]
López de Romaña D. Situación actual de los micronutrientes en Latinoamérica: Prevalencia de su deficiencia y programas nacionales de entrega de micronutrientes. Presentación en el 1.er Evento para la Fortificación del Arroz en América Latina y el Caribe. Santo Domingo: Programa Mundial de alimentos de las Naciones Unidas. 2016. 28 p. [acceso 28/10/2016]. Disponible en:http://es.wfp.org/sites/.../1_situacion_actual_de_los_micronutrientes_en_latinoamerica.pdf]
Malavolta M, Piacenza F, Basso A, Giacconi R, Costarelli L, Mocchegiani E. Serum copper to zinc ratio: Relationship with aging and health status. Mechanisms of Ageing and Development. 2015 acceso 29/04/2016;151:93-100. Disponible en: https://www.sciencedirect.com/science/article/pii/SO047637415000068/pdfft?md5=b3211f929daf1a1840588cad3a1b619d&pid=1S-2.0- SO 047637415000068-main.pdf]
Borja-Magno A, Mujica-Coopman MF, Pizarro Aguirre F, Olivares Grohnert M. Efecto de la suplementación combinada con hierro y cinc sobre el estado nutricional de cobre en mujeres de edad reproductiva. Rev Chil Nutr. 2014 [acceso 29/08/2015];41(4):391-98. Disponible en: https://scielo.conicyt.cl/pdf/rchnut/v41n4/art07.pdf]
World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System (VMNIS) Geneva: World Health Organization; 2011. [acceso 28/02/2019]. Disponible en: Disponible en: https://www.who.int/vmnis/indicators/haemoglobin/]
Thurnham DI, McCabe LD, Haldar S, Wieringa FT, Northrop-Clewes CA, McCabe GP. Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis. Am J Clin Nutr. 2010 [acceso 05/05/2017];92(3):546-55. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/20610634]
Declaración de Helsinki de la Asociación Médica Mundial. Principios éticos para las investigaciones médicas en seres humanos. 64.a Asamblea General, Fortaleza, Brasil; Madrid: Instituto de Salud Carlos III; 2013.9 p. [acceso 09/11/2016]. Disponible en: Disponible en: https://www.wma.net/.../declaracion-de-helsinki-de-la-amm-principios-eticos-para-las-...]
Cruz Manzano E, Sánchez Domínguez E, Paredes Pérez MC, Álvarez Ramírez D, Céspedes Miranda EM. Consumo y niveles séricos de micronutrientes en adultos mayores de un consultorio médico de familia. Rev Cub Sal Públ. 2003 [acceso 09/11/2016];29(2):117-20. Disponible en: http://www.scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-34662003000200004 http://www.scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30432017000400005]
Ballesteros Hernández M, Guirado Blanco O, Alfonso Rodríguez J, Marrero Martínez JA, Fernández Caraballo D, Heredia Ruiz D. Concentraciones de oligoelementos y reactividad vascular en mujeres en edades fértiles y posmenopáusicas. Medicentro. 2017 [acceso 07/02/2018];21(4). Disponible en: http://www.scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30432017000400005]
Taboada Lugo N, Mollineda Trujillo A, Herrera Martínez M, Algora Hernández AE, Noche González G, Noa Machado I. Niveles séricos de cinc y cobre en madres con descendencia afectada por defectos del tubo neural. Rev Cubana Pediatr. 2017 [acceso 07/02/2018];89(3):299-309. Disponible en: http://www.scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75312017000300004]
Jiménez Acosta SM, Martín González I, Rodríguez Suárez A, Silvera Téllez D, Núñez Torres E, Alfonso Fagué K. Prácticas de alimentación en niños de 6 a 23 meses de edad. Rev Cubana Pediatr. 2018 acceso 14/01/2019;90(1). Disponible en: http://www.revpediatria.sld.cu/index.php/ped/article/view/383/175]
McMillan DC, Maguire D, Talwar D. Relationship between nutritional status and the systemic inflammatory response: micronutrients. Proc Nutr Soc. 2019 [acceso 05/07/2019];78(1):56-67. Disponible en: https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/relationship-between-nutritional-status-and-the-systemic-inflammatory-response-micronutrients/3E59EF52136C08210A07DBB749C5AF22]
Ballesteros Hernández M, Rodríguez JA, Guirado Blanco O, González Paz H, Pérez de Armas A, Mollineda Trujillo A. Concentraciones séricas de los oligoelementos hierro, cobre y cinc en individuos normotensos, hiperreactivose hipertensos. Medicentro. 2011 acceso 09/11/2016;15(2):140-145. Disponible en:]
Wade S, Idohou-Dossou N, Diouf Al. Adjusting plasma zinc concentrations of ferritin, retinol, and zinc affect the prevalence of micronutrient deficiencies in children butnot in women. Ann Nutr Metab. 2013 [acceso 14/04/2015];63(suppl 1):821. Disponible en: https://izincg.squarespace.com/s/Senegal_Abstract.pdf]
Fedra LM, Cabré N, Nadal M, García Heredia A, Baiges Gaya G, Hernández Aguilera A, et al. Serum concentrations of trace elements and their relationships with paraoxonase-1 in morbidly obese women. J Trace ElemMedBio. 2018 [acceso 27/02/2019];48:8-15. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0946672X17310192]