medigraphic.com
ISSN 1561-3127 (Electronic)
ISSN 0864-3466 (Print)

2020, Number 3

<< Back Next >>

Revista Cubana de Salud Pública 2020; 46 (3)

Acute manifestations in the infection by Chikungunya virus in a city of Colombia

Jimenez-Canizales CE, Sarmiento-Ospina AL, Chavarro-Ordoñez R, Vasquez-Serna H, Lasprilla-Urrego MI, Montero-Cruz E

Language: Spanish
References: 28
Page: 1-17
PDF size: 852.44 Kb.


ABSTRACT

Introduction: The acute infection by Chikungunya generates a high burden of illness and disability mainly due to polyarthralgias in acute phase and artritis in chronic phase. However, it presents symptoms similar to other arboviruses, specially like dengue, which difficults its diagnosis.
Objective: To characterize the clinical manifestations of the acute infection by Chikungunya in patients attended in the emergencies service of Ibagué city, Colombia, during the epidemic outbreak that occured from October, 2015 to October, 2016.
Methods: Descriptive, cross-sectional study in which were described the clinical manifestations of the acute infection by chikungunya using an instrument developed from the review of the literature that comprises the main clinical manifestations of the infection by chikungunya in its acute phase, as an information attached to the epidemiologic records of individual obligatory notification of the National Institute of Health, which are reported to Ibagué-Tolima Municipal Secretary.
Results: There were collected 6752 records of patients attended in emergency services, whom experienced fever of 38,5 ºC from 1 to 7 days (91,3%), myalgias (81,3%), maculopapular erythema (74,3%), severe arthralgias (70,6%), polyarthritis (41,1%) and retroarticular adenomegalies (8%).
Conclusions: The results obtained in the present study provide important information for the clinical diagnosis of chikungunya in places with similar characteristics to the hyperepidemic cities and it facilitates to differentiate the disease in its acute phase among the different current arboviruses with signs of myalgia, retroarticular adenopathies and severe arthralgia.


REFERENCES

  1. Wilder-Smith A, Gubler DJ, Weaver SC, Monath TP, Heymann DL, Scott TW. Epidemic arboviral diseases: priorities for research and public health.Lancet Infect Dis; 2016;17(3):e101-e6. DOI: 10.1016/S1473-3099(16)30518-7

  2. Organizacion Panamericana de la Salud. Número de casos reportados de Chikunguya en países o territorios de las Américas 2016 (por semanas). Washington D.C.: OPS; 2016 [acceso 15/01/2017]. Disponible en: Disponible en: http://www.paho.org/hq/index.php?option=com_docman&task=doc_download&Itemid=270&gid=37633&lang=en

  3. Krishnamoorthy K, Harichandrakumar K, Kumari AK, Das L. Burden of chikungunya in India: estimates of disability adjusted life years (DALY) lost in 2006 epidemic. Journal of vector borne diseases. 2009;46(1):26. Disponible en: https://pubmed.ncbi.nlm.nih.gov/19326705/

  4. Cardona-Ospina JA, Villamil-Gomez WE, Jimenez-Canizales CE, Castaneda-Hernandez DM, Rodriguez-Morales AJ. Estimating the burden of disease and the economic cost attributable to chikungunya, Colombia, 2014. Trans R Soc Trop Med Hyg. 2015;109(12):793-802. DOI: 10.1093/trstmh/trv094

  5. Grupo SIVIGILA y Estadísticas Vitales Departamentales. Boletín Epidemiológico Semanal Tolima. Semana epidemiológica No.48. 27 de Noviembre al 3 de Diciembre 2016. Ibagué: Secretaría de salud departamental, gobernacion del Tolima; 2016 [acceso 02/02/2017]. Disponible en: Disponible en: http://www.saludtolima.gov.co/boletin-epidemiologico-sivigila-tolima/

  6. Pialoux G, Gaüzère B-A, Jauréguiberry S, Strobel M. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis. 2007;7(5):319-27. DOI: 10.1016/S1473-3099(07)70107-X

  7. Thiberville SD, Moyen N, Dupuis-Maguiraga L, Nougairede A, Gould EA, Roques P, et al. Chikungunya fever: Epidemiology, clinical syndrome, pathogenesis and therapy. Antiviral Res. 2013;99(3):345-70. DOI: 10.1016/j.antiviral.2013.06.009

  8. Mattar S, Miranda J, Pinzon H, Tique V, Bolanos A, Aponte J, et al. Outbreak of Chikungunya virus in the north Caribbean area of Colombia: clinical presentation and phylogenetic analysis. J Infect Dev Ctries. 2015;9(10):1126-32. DOI: 10.3855/jidc.6670

  9. Goupil BA, Mores CN. A Review of Chikungunya Virus-induced Arthralgia: Clinical Manifestations, Therapeutics, and Pathogenesis. Open Rheumatol J. 2016;10:129-40. DOI:10.2174/1874312901610010129

  10. Pastula DM, Hancock WT, Bel M, Biggs H, Marfel M, Lanciotti R, et al. Chikungunya virus disease outbreak in yap state, federated states of Micronesia. PLoS neglected tropical diseases. 2017;11(3):e0005410. DOI: 10.1371/journal.pntd.0005410

  11. van Genderen FT, Krishnadath I, Sno R, Grunberg MG, Zijlmans W, Adhin MR. First Chikungunya Outbreak in Suriname; Clinical and Epidemiological Features. PLoS Negl Trop Dis. 2016;10(4):e0004625. DOI: 10.1371/journal.pntd.0004625

  12. Cardoso CW, Paploski IA, Kikuti M, Rodrigues MS, Silva MM, Campos GS, et al. Outbreak of exanthematous illness associated with Zika, chikungunya, and dengue viruses, Salvador, Brazil. Emerging infectious diseases. 2015;21(12):2274.

  13. Javelle E, Ribera A, Degasne I, Gauzere BA, Marimoutou C, Simon F. Specific management of post-chikungunya rheumatic disorders: a retrospective study of 159 cases in Reunion Island from 2006-2012. PLoS Negl Trop Dis. 2015;9(3):e0003603. DOI: 10.1371/journal.pntd.0005410

  14. Zeana C, Kelly P, Heredia W, Cifuentes A, Franchin G, Purswani M, et al. Post-chikungunya rheumatic disorders in travelers after return from the Caribbean. Travel Med Infect Dis. 2016;14(1):21-25. DOI: 10.1016/j.tmaid.2016.01.009

  15. Lineamientos de vigilancia en salud pública, entomológica y de laboratorio en transmisión autóctona del virus chikungunya en Colombia fase II. Colombia: Instituto Nacional de Salud/Ministerio de Salud; 2014[acceso 02/02/2018]. Disponible en: Disponible en: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/VS/PP/ET/Anexo%203%20Lineamientos%20de%20Vigilancia%20CHIKV%202014.pdf 2014

  16. Organización Panamericana de la Salud. Instrumento para el diagnóstico y la atención a pacientes con sospecha de arbovirosis.. Washington, D.C: OPS; 2016.

  17. Grupo SIVIGILA, Estadísticas Vitales Departamentales. Boletín Epidemiológico Semanal. Semana epidemiológica No.39. 27 sep. al 03 oct. 2015 [acceso 27/02/2018]. Bogotá: Instituto Nacional de Salud/Ministerio de Salud; 2015 Disponible en: Disponible en: https://www.ins.gov.co/buscador-eventos/BoletinEpidemiologico/2015%20Boletin%20epidemiologico%20semana%2039.pdf.

  18. Simon F, Javelle E, Cabie A, Bouquillard E, Troisgros O, Gentile G, et al. French guidelines for the management of chikungunya (acute and persistent presentations). November 2014. Med Mal Infect. 2015;45(7):243-63. DOI: 10.1016/j.medmal.2015.05.007

  19. Yactayo S, Staples JE, Millot V, Cibrelus L, Ramon-Pardo P. Epidemiology of Chikungunya in the Americas. J Infect Dis. 2016;214(suppl 5):S441-S5. DOI: 10.1093/infdis/jiw390

  20. Powers AM, Logue CH. Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus. J Gen Virol. 2007;88(Pt 9):2363-77. DOI: 10.1099/vir.0.82858-0

  21. da Cunha RV, Trinta KS. Chikungunya virus: clinical aspects and treatment-A Review. Mem. Inst. Oswaldo Cruz. 2017;112(8):523-31. DOI: https://doi.org/10.1590/0074-02760170044

  22. Restrepo-Jaramillo BN. Infección por el virus del Chikungunya. CES Med. 2014 [acceso 31/07/2020];28(2):313-23. Disponible en: Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-87052014000200016&lng=en

  23. Cardona-Ospina JA, Jiménez-Canizales CE, Vásquez-Serna H, Garzón-Ramírez JA, Alarcón-Robayo JF, Cerón-Pineda JA, et al. Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas. Trop Med Infect Dis. 2018;3(4):123. DOI: 10.3390/tropicalmed3040123

  24. Rajapakse S, Rodrigo C, Rajapakse A. Atypical manifestations of chikungunya infection. Trans R Soc Trop Med Hyg. 2010;104(2):89-96. DOI: 10.1016/j.trstmh.2009.07.031

  25. Bonifay T, Prince C, Neyra C, Demar M, Rousset D, Kallel H, et al. Atypical and severe manifestations of chikungunya virus infection in French Guiana: A hospital-based study. PLoS One. 2018;13(12):e0207406. DOI: 10.1371/journal.pone.0207406.

  26. Ramful D, Carbonnier M, Pasquet M, Bouhmani B, Ghazouani J, Noormahomed T, et al. Mother-to-child transmission of Chikungunya virus infection. Pediatr Infect Dis J. Sep 2007;26(9):811-5. DOI: 10.1097/INF.0b013e3180616d4f

  27. Senanayake MP, Senanayake SM, Vidanage KK, Gunasena S, Lamabadusuriya SP. Vertical transmission in chikungunya infection. Ceylon Medical Journal. 2009;54(2):47-50. DOI: 10.4038/cmj.v54i2.865.

  28. MinSalud. Boletín de Prensa No 274 de 2015: MinSalud confirma primeros nueve casos de zika en Colombia, Bogota, Ministerio de Salud y protección social; 2015 [acceso 05/03/2017]. Disponible en: Disponible en: https://www.minsalud.gov.co/Paginas/Confirmados-primeros-casos-de-virus-del-zika-en-Colombia.aspx




2020     |     www.medigraphic.com