Gomes PF, de Lima MD, Silva AAC, Marquete R, Mansur E

Language: Portugués
References: 20
Page: 1-11
PDF size: 591.90 Kb.

ABSTRACT

Introduction: The species Casearia sylvestris Sw. is used by the population as a medicinal plant. This species is included in the National List of Medicinal Plants of Interest to the Unified Health System.
Objective: Evaluate the seasonal study of the species C. sylvestris at Tijuca National Park.
Methods: Essential oils were extracted by hydrodistillation in a modified Clevenger device for two hours in all seasons. Analysis was conducted by gas chromatography / mass spectrometry and gas chromatography with flame detector.
Results: The composition of the most abundant compounds in the oil (germacrene B, γ-elemene and β-elemene) was not found to change throughout the one-year period. Therefore, seasonal studies about the species C. sylvestris are essential, included as it is in the National List of Medicinal Plants of Interest to the Unified Health System. No information is available about studies of this sort to detect variations in active components which may compromise the use of this species as a medicinal plant in the country, as well as raw material for biotechnological products.
Conclusion: The chemical profile of the essential oil from C. sylvestris collected in Rio de Janeiro differs from that of other specimens collected from other states in Brazil, and no variations were found in the composition of the oil as to the most abundant compounds.

REFERENCES

1. Sleumer HO. Flora Neotropica Monograph n.22 (Flacourtiaceae). New York: The New York Botanical Garden; 1980.

2. Rossi M, Mattos IFA, Coelho RM, Menk JRF, Rocha FT, Pfeifer RM, et al. Relação solos/vegetação em área natural no Parque Estadual de Porto Ferreira, São Paulo. Rev Inst Flor. 2005;17(1):45-61.

3. Thadeo M, Azevedo AA, Meira RMSA. Foliar anatomy of neotropical Salicaceae: potentially useful characters for taxonomy. Plant Syst Evol. 2014;300(9):2073-89.

4. Marquete R, Mansano VF. A new species of Casearia (Salicaceae) from Brazil. J Sys Evol. 2013;51(2):228-29.

5. Ferreira PMP, Militão GCG, Lima DJB, Costa NDJ, Machado KC, Dos Santos AG, et al. Morphological and biochemical alterations activated by antitumor clerodane diterpenes. Chem Biol Interact. 2014;222:112-25.

6. Ferreira PMP, Bezerra DP, Silva JN, Costa MP, Ferreira JRO, Alencar NMN, et al. Preclinical anticancer effectiveness of a fraction from Casearia sylvestris and its component Casearin X: in vivo and ex vivo methods and miscroscopy examinations. J Ethnopharmacol. 2016;186:270-79.

7. Esteves I, Souza IR, Rodrigues M, Cardoso LG, Santos LS, Sertie JA, et al. Gastric antiulcer and anti-inflamatory activities of the essential oil from Casearia sylvestris Sw. J Ethnopharmacol. 2005;101(1-3):191-6.

8. Tininis AG, Assonuma AA, Telascrea M, Perez CC, Silva MRSRM, Favoreto R, Cavalheiro AJ. Composição e variabilidade química de óleo essencial de Casearia sylvestris Sw. Revista Brasileira de Plantas Medicinais, Botucatu. 2006;8(4):132-36.

9. Sousa FG, Schneider FZ, Mendes CE, Moura NF, Denardin RBN, Matuo R, et al. Clastogenic and anticlastogenic effect of the essential oil from Casearia sylvestris Swartz. J Essent Oil Res 2007;19:376-78.

10. Silva SL, Chaar JS, Figueiredo PMS, Yano T. Cytotoxic evaluation of essential oil from Casearia sylvestris Sw. on humam cancer cells and erythrocytes. Acta Amaz. 2008;38(1):107-12.

11. Bou DD, Lago JH, Figueiredo CR, Matsuo AL, Guadagnin RC, Soares MG, et al. Chemical composition and cytotoxicity evaluation of essential oil from leaves of Casearia sylvestris, its main compound α-zingiberene and derivatives. Molecules. 2013;18(8):9477-87.

12. Pereira FG, Costa FB, Marquete R, May B, Falcão DQ, Mansur E, et al. Anti-herpes activities of the pure and nanoemulsion of essential oil from leaves of Casearia sylvestris Sw. (SALICACEAE). IJGHC. 2016;5(2B):112-21.

13. Pereira FG, Marquete R, Domingos LTS, Rocha MEN, Ferreira-Pereira A, Mansur E, et al. Antifungal activities of the essential oil and its fractions rich in sesquiterpenes from leaves of Casearia sylvestris Sw. An Acad Bras Cienc. 2017;89:2817-24.

14. Gobbo-Neto L, Lopes NP. Plantas medicinais: fatores de influência no conteúdo de metabólitos secundários. Quim Nova. 2007;30(2):374-81.

15. Adams RP. Identification of Essential Oil Components by Gas Chromatography/Quadrupole Mass Spectroscopy.3rd Ed. Carol Stream, Illinois: Allured Publishing; 2001.

16. Sistema Alerta Rio. 2016 [acesso: 25/10/2016]. Disponible en: http://websempre.rio.rj.gov.br/estacoes/

17. Berardi AE, Fields PD, Abbate JL, Taylor DR. Elevational divergence and clinical variation in floral color and leaf chemistry in Silene vulgaris. Am J Bot. 2016;103(8):1508-23.

18. Pinheiro CG, Machado CM, Amaral LP, Silva DT, Almeida CA, Longhi SJ, et al. Seasonal variability of the essential oil of Hesperozygis ringens (Benth.) Epling. Braz J Biol. 2016;76(1):176-84.

19. Schneider NFZ, Moura NF, Colpo TA. Composição química e atividade antimicrobiana do óleo volátil de Casearia sylvestris. Rev Bras Farmacogn. 2006;87(4):112-14.

20. Pezzi A. Análise Quali-quantitativa do óleo essencial, sua ação fungicida in vitro sobre fitopatógenos e estudo sobre rizogênese [dissertação]. Brasil: Universidade Federal do Rio Grande do Sul; 2014.