2021, Number 4
<< Back Next >>
Acta Med 2021; 19 (4)
Global longitudinal strain relation with diastolic dysfunction degree, cardiovascular risk factors and 2D echocardiogram variables
Sánchez LF, Domínguez CLG, Rivas LSC, Flores PD
Language: Spanish
References: 26
Page: 485-490
PDF size: 184.58 Kb.
ABSTRACT
Introduction: Prognosis in patients with cardiovascular structural disease largely depends on the left ventricular function quality; the measurement of myocardial deformation (strain) is an earlier and more sensitive indicator of heart failure.
Objective: To correlate the left ventricle diastolic dysfunction degree and other 2D echocardiogram variables with the global longitudinal strain (SLG).
Material and methods: 53 patients with an average age and SD of 59.8 years ± 17.5 and a range of 22 to 91 years were studied, in which routine echocardiographic and SLG measurements were made. Statistical analysis: χ
2, t Student, and odds ratio were used to assess the relationship of the variables with the SLG.
Results: In all cases where diastolic dysfunction was found characterized by prolonged relaxation or pseudo normal filling pattern the SLG was subnormal; likewise, in all cases with concentric remodeling, concentric and eccentric hypertrophy, as well as with the presence of left atrial dilation; in the same way in all cases where risk factors were found (female gender, systemic hypertension, diabetes, dyslipidemia, and smoking) the SLG index was subnormal.
Conclusions: The reduction of global longitudinal strain correlates with the degree of diastolic dysfunction, abnormalities in conventional echocardiographic measurements, as well as the presence of cardiovascular risk factors, all of which should be considered as adverse prognostic predictors.
REFERENCES
GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015; 385(9963): 117-171.
Park JJ, Park JB, Park JH, Cho GY. Global longitudinal strain to predict mortality in patients with acute heart failure. J Am Coll Cardiol. 2018; 71(18): 1947-1957. doi: 10.1016/j.jacc.2018.02.064.
Sherazi S, Zareba W. Diastolic heart failure: predictors of mortality. Cardiol J. 2011; 18(3): 222-232.
Díaz Herrera W, Rincón Flórez DF, Martínez Montalvo CM. Evaluación de la disfunción diastólica y consideraciones perioperatorias. Acta Méd Peru. 2017; 34(3): 208-216.
Sánchez-Lezama F, Domínguez-Carrillo LG, Harrison-Gómez C, Ramírez-Lagundas M. Clinical and echocardiographic variables associated to left atrium enlargement. Differences between genders. Cardiovasc Metab Sci. 2019; 30(1): 6-13.
Del Castillo JM, Herszkowicz N, Ferreira C. Speckle tracking. A contratilidade miocárdica em sintonia fina. Rev Bras Ecocardiogr Imagem Cardiovasc. 2010; 23(3): 46-54.
Mondillo S, Galderisi M, Mele D, Cameli M, Lomoriello VS, Zaca V et al. Speckle-tracking echocardiography: a new technique for assessing myocardial function. J Ultrasound Med. 2011; 30(1): 71-83.
Cuevas RJ, Lacambra BI. Ecocardiografía avanzada: aplicación clínica actual del análisis de deformación miocárdica y de la imagen tridimensional. Rev Ecuat Med Cienc Biol. 2017; 38(2): 67-83. Disponible en: doi.org/10.26807/remcb.v38i2.550
Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol. 1986; 57(6): 450-458.
D'hooge J, Heimdal A, Jamal F, Kukulski T, Bijnens B, Rademakers F et al. Regional strain and strain rate measurements by cardiac ultrasound: principles, implementation and limitations. Eur J Echocardiogr. 2000; 1(3): 154-170.
Urheim S, Edvardsen T, Torp H, Angelsen B, Smiseth OA. Myocardial strain by Doppler echocardiography. Validation of a new method to quantify regional myocardial function. Circulation. 2000; 102(10): 1158-1164.
Yingchoncharoen T, Agarwal S, Popovi? ZB, Marwick TH. Normal ranges of left ventricular strain: a meta-analysis. J Am Soc Echocardiogr. 2013; 26(2): 185-191.
Rodríguez BI, Jiménez NM, Pérez GR, García OR, Morillo VE, de Teresa GE. Deformación ventricular izquierda en ecocardiografía bidimensional: valores y tiempos en sujetos normales. Rev Esp Cardiol. 2010; 63(10): 1195-1199. doi: 10.1016/S0300-8932(10)70252-9.
Voigt JU, Pedrizzetti G, Lysyansky P, Marwick TH, Houle H, Baumann R et al. Definitions for a common standard for 2D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. Eur Heart J Cardiovasc Imaging. 2015; 16(1): 1-11.
Cheng S, Larson MG, McCabe EL, Osypiuk E, Lehman BT, Stanchev P et al. Age- and sex-based reference limits and clinical correlates of myocardial strain and synchrony: the Framingham Heart Study. Circ Cardiovasc Imaging. 2013; 6(5): 692-699.
Villarroel-Ábrego H, Garillo R, González-Suero JC, Núñez AE. Correlación entre fracción de eyección del ventrículo izquierdo y strain longitudinal global en pacientes con hipertensión arterial. Insuf Card. 2018; 13(2): 57-66.
Ng AC, Delgado V, Bertini M, van der Meer RW, Rijzewijk LJ, Shanks M et al. Findings from left ventricular strain and strain rate imaging in asymptomatic patients with type 2 diabetes mellitus. Am J Cardiol. 2009; 104(10): 1398-1401.
Faden G, Faganello G, De Feo S, Berlinghieri N, Tarantini L, Di Lenarda A et al. The increasing detection of asymptomatic left ventricular dysfunction in patients with type 2 diabetes mellitus without overt cardiac disease: data from the SHORTWAVE study. Diabetes Res Clin Pract. 2013; 101(3): 309-316.
Holland DJ, Marwick TH, Haluska BA, Leano R, Hordern MD, Hare JL et al. Subclinical LV dysfunction and 10-year outcomes in type 2 diabetes mellitus. Heart. 2015; 101(13): 1061-1066.
Vinereanu D, Nicolaides E, Tweddel AC, Madler CF, Holst B, Boden LE et al. Subclinical left ventricular dysfunction in asymptomatic patients with Type II diabetes mellitus, related to serum lipids and glycated haemoglobin. Clin Sci (Lond). 2003; 105(5): 591-599.
Saito M, Okayama H, Yoshii T, Higashi H, Morioka H, Hiasa G et al. Clinical significance of global two-dimensional strain as a surrogate parameter of myocardial fibrosis and cardiac events in patients with hypertrophic cardiomyopathy. Eur Heart J Cardiovasc Imaging. 2012; 13(7): 617-623.
Pinto M. Strain: una ventana a la mecánica ventricular. Rev Chil Cardiol. 2011; 30(2): 155-159.
Cañón-Montañez W, Santos A, Foppa M. Strain longitudinal global: un parámetro útil para evaluar disfunción ventricular izquierda subclínica en el síndrome metabólico. Rev Colomb Cardiol. 2016; 23(2): 112-119. Disponible en: http://dx.doi.org/10.1016/j.rccar.2015.10.008
Herrera-Márquez R, Peralta-Cortázar C, Contreras-Rodríguez A, Hernández-Rodríguez J, Manjarrez-Gutiérrez G. Disfunción diastólica subclínica del ventrículo izquierdo en adolescentes con diabetes tipo 1. Bol Med Hosp Infant Mex. 2014; 71(3): 142-147.
Salazar-Marín S, Valencia JM, Hernández-Vásquez OM, Estrada JM. Utilidad del strain sistólico pico longitudinal bidimensional en pacientes con diagnóstico clínico de infarto del miocardio sin elevación del ST. Rev Colomb Cardiol. 2017; 24(6): 550-558.
Reborido N, Parma G, Noria S, Schiavone A, Bonelli A, Lluberas R. Strain bidimensional para detección precoz de disfunción sistólica del ventrículo izquierdo inducida por agentes quimioterápicos. Rev Urug Cardiol. 2016; 31(2): 266-276.