2021, Number 3
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Dermatología Cosmética, Médica y Quirúrgica 2021; 19 (3)
Cutaneous and histopathological characteristics in patients with severe sars-cov-2 infection
Lemini LA, Cruz FED, Gamboa JTI, Hernández PF, Pérez CAE, Arreola RRL, Valverde GYA, Durón VD, Mejía MCG, Franco PMV, Juárez AFG, Flores PG, Eligio ÁM, Aguilar UMA, Castellanos PLG, Hop GK, Anides FAE
Language: Spanish
References: 11
Page: 228-233
PDF size: 354.58 Kb.
ABSTRACT
Skin manifestations due to sars-cov-2 have been reported in
different countries. In Mexico, it has been published that urticaria
and maculopapular rashes are the most frequent associated
dermatosis.
Objetive: to describe the cutaneous manifestations and their
histopathological characteristics in Mexican patients with sarscov-
2 infection at the Hospital de Especialidades, Centro Médico
Nacional Siglo xxi, imss from March 15, 2020 to October 15,
2020.
Material and methods: We carried out a retrospective,
cross-sectional and descriptive study of patients diagnosed
with covid-19 who were hospitalized in the covid area. Patients
older than 18 years were included, with a positive test for sarscov-
2, who presented a dermatological manifestation and skin
biopsy was performed for histopathological studies with hematoxylin-
eosin and immunohistochemistry for c4d and langerina.
Results: twelve patients with covid-19 associated dermatosis
who underwent skin biopsy were included. In 50% they were
localized-dermatoses with a greater affection to the lower
limbs, characterized by purpuric dermatoses in half of the cases.
Conclusions: the clinical-pathological correlation could not
be established, not the association between proinflammatory
and thrombotic laboratory indicators with histopathology due
to the reduced sample size. Even so, our study provides both
clinical and histopathological characteristics in patients hospitalized
for severe covid.
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