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ISSN 1561-3070 (Electronic)

2020, Number 2

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Rev Cub Oftal 2020; 33 (2)

Photoactivated chromophore with crosslinking as treatment for Acanthamoeba keratitis

Garduño VL, De la Fuente-Batta I, Hernández-Da Mota SE, Zavala-Martínez MT

Language: Spanish
References: 10
Page: 1-8
PDF size: 349.46 Kb.


ABSTRACT

A report is presented of the use of crosslinking as treatment for Acanthamoeba keratitis in a series of 7 patients attending the Cornea Service for multitreated keratitis. Corneal biopsy was performed, which was cultured in Page solution. The patients were treated with a PACK-CXL protocol for more than 5 minutes and subjected to UV-A light exposure. Edema of the new epithelium was 2 crosses at 24 hours and disappeared 2 weeks after the procedure in all cases. Basal de-epithelialization percentage at diagnosis was 75.7%. Best corrected visual acuity ranged between 20/20 and 20/30. It is concluded that the use of crosslinking in patients with Acanthamoeba keratitis in its initial stages could be a safe and effective therapeutic option.


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