2021, Number 2
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Rev Odotopediatr Latinoam 2021; 11 (2)
Green deciduous teeth due to hyperbilirubinemia
Raposo IA, Matos RM, Souto de Araujo MV, Tedesko TK, Imparato, JCPI
Language: Spanish
References: 22
Page: 315-325
PDF size: 514.03 Kb.
ABSTRACT
Defined as a serum bilirubin concentration, hyperbilirubinemia is a rare condition and can be caused by any factor that raises the bilirubin load to be metabolized by the liver. Thus, bilirubin is distributed throughout the body’s tissues and accumulates in hard tissues, including primary teeth. The aim of this work is to report a clinical case about the severe repercussion of hyperbilirubinemia in primary teeth, and its early childhood manifestations, such as greenish teeth. A male patient, 3 years and 8 months old, attended the dental clinic for evaluation of “green spots on teeth”. Medical history revealed that the child had premature birth and postpartum complications that evolved into sepsis, and due to the use of several drugs, developed hyperbilirubinemia. The dental clinical examination showed the presence of green spots on all 20 deciduous teeth, absence of carious lesions, healthy gums and good oral hygiene conditions. We conclude
that the high levels of bilirubin developed by the premature child, associated with septicemia can lead to green pigmentation (intrinsic staining) in primary teeth and affect the permanent teeth. Therefore, knowledge of the medical history of the child from birth is relevant to the establishment of diagnoses and prognoses of dental changes.
REFERENCES
Watanabe K, Shibata T, Kurosawa T, Morisaki I, Kinehara M, Igarashi S, et al. Bilirubin pigmentation of human teeth caused by hyperbilirubinemia. J Oral Pathol Med. 1999; 28:128-30.
Almeida E. Pigmentação verde da dentição primária associada à hiperbilirrubinemia no período neonatal. Revista Científica FMC. 2011; 6: 8-10.
Najib KS, Saki F, Hemmati F, Inaloo S. Incidence, risk factors and causes of severe neonatal hyperbilirubinemia in the South of iran (fars province). Iran Red Crescent Med J. 2013 Mar;15(3):260-3.
Battineni S, Clarkep. Green teeth are a late complication of prolonged conjugated hyperbilirubinemia in extremely low birth weight infants. Red Dent. 2012; 34 (4): 103:6
Kyung PM, Sun Y, Kang CM, Lee H, Seon CJ. Green Teeth Associated Hyperbilirubinemia in Primary Dentition. J Korean Acad Pediatr Dent 2017; 44(3): 378-383.
Silva JEO. Dentes esverdeados em paciente com colestase neonatal: relato de caso clínico [monografia]. Manaus: Instituto de Ciências da Saúde Funorte/Soebras; 2012.
Zaia AA, Graner E, De Almeida OP. Oral changes associated with biliary atresia and liver transplantation. J ClinPediatr Dent 1993; 18: 39-42.
O’Connor MJ. Mechanical biliary obstruction. A review of the multisystemic consequences of obstructive jaundice and their impact on perioperative morbidity and mortality. Am Surg 1985; 51: 245-51.
Silva RN , Alves FA, Antunes A, Vai MF, Giannini M, Tenório MD, Machado JL, Paes-Leme AF, Lopes MA, e Silva ARS. Decreased dentin tubules density and reduced thickness of peritubular dentin in hyperbilirubinemia-related green teeth. J Clin Exp Dent. 2017 May; 9(5): e622–e628.
Do Valle IB, E VM, Goese TB, Oliveira ZFL, SandraVentorin von Zeidler. Green Teeth in the Primary and Permanent Dentition. J Pediatr 2017;191:275.
Canela AHC, Rezende KMPC, Carrilho SR, Arana-Chavez V.E, Bönecker M. Hyperbilirubinemia and intrinsic pigmentation in primary teeth. A case report and histological findings.. Pediatric and Developmental Pathology (Print), v. 14, p. in press, 2011.
Sommer S, Magagnin K, Kramer PF, Tovo MF, Bervian J. Green teeth associated with neonatal hyperbilirubinemia caused by biliary atresia: review and case report. J Clinic Pediatr Dent. 2010; 35: 199-202.
Rangé H, Camy S, Cohen J, Colon P, Bouchard P. Dental treatment of an adult patient with a history of biliary atresia. Quintessence Int. 2012;43(4):337-41.
Sandoval MJ, Zekeridou A, Spyropoulou V, Courvoisier D, Mombelli A, McLin V, Giannopoulou C. Oral health of pediatric liver transplant recipients. Pediatric Transplantation. 2017;21:e13019.
Rosenthal P, Ramos A, Mungo R. Management of children with hyperbilirubinemia and green teeth. J Pediatr 1986; 108: 103-5.
Fernandes KS, Magalhães M, Ortega KL. Green teeth. J Pediatr. 2011; 158: 510.
Silva Filho OG, Garib DG, Lara TS. Ortodontia interceptiva. Protocolo de tratamento em duas fases. Ed Artes Medicas.2013
Alto L, Pomarico L, Souza IPR. Green pigmentation of deciduous teeth: report of two cases. J Dent Child (Chic). 2004; 71: 179-82.
Barbério GS, Zingra ACG, Santos PSS, Machado MAAM. Green Teeth Related to Bilirubin Levels. Acta stomatol Croat. 2018;52(1):61-64.
Lin YT, Lin YT, Chen CL. A Survey of the oral status of children undergoing liver transplantation. Chang Gung Med J. 2003; 26: 184-8.
Vivas APM. Avaliação de manifestações bucais em pacientes pediatricos submetidos ao transplante hepatico (dissertação). São Paulo: USP/FO;2012.
Patil SB, Hugar S, Patil S. Green teeth associated with hyperbilirubinemia: A case report. European Archives of Paediatric Dentistry. 2014; 15(2 suppl):221-223