2021, Number 2
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Rev Odotopediatr Latinoam 2021; 11 (2)
Langerhans cell histiocytosis: 5-year follow-up and systematic literature review
Medina RB, Arocho L, López Del-Valle LM, Molina-Negrón D
Language: Spanish
References: 13
Page: 306-314
PDF size: 482.07 Kb.
ABSTRACT
Langerhans cell histiocytosis (LCH) is a rare disease characterized by aggressive clonal proliferation of dendritic Langerhans cells from the bone marrow. The disease creates osteolytic lesions where oral manifestations are usually present. The objective of this case report is to present the five-year follow-up of a case diagnosed in 2014 and a systematic review of the literature on the oral manifestations of LCH. For the systematic review, the search argument with keywords such as LCH, histiocytosis X and oral manifestations, were conducted in five databases such as PUBMED, LILACS, EBSCO, OVID and SCOPUS. The most common oral manifestations are inflammation, redness, and bone loss in the affected areas. It is important to regularly monitor LCH cases in the pediatric population in the dental office. LCH usually presents oral manifestations that can be an early diagnostic sign of this condition, especially in the pediatric population.
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