2020, Number 3
Bacterial infections associated with COVID-19 in patients of the Intensive Care Unit
Language: Spanish
References: 13
Page:
PDF size: 257.23 Kb.
ABSTRACT
Introduction: The first reports from China suggested that coinfection with other pathogens in COVID-19 was abnormal, the latest evidence has shown that other infections may appear, especially in severe patients.Objective: To describe the bacterial infections associated with COVID-19, in patients in an intensive care unit.
Methods: A descriptive study was carried out in the period from March 24 to May 24, 2020, in the intensive care unit of the Military Hospital "Comandante Manuel Fajardo Rivero". The study population consisted of 13 patients from 49 to 91 years, those who remained hospitalized in that room, with a confirmed diagnosis, by the real-time reverse transcriptase-polymerase chain reaction test for SARS-CoV-2. The study variables were: age, sex, clothing, personal pathological history, status at discharge, isolated microorganisms and antimicrobial susceptibility.
Results: 61.5% of the patients were female, the mean age was 78.8 years, 61.5% died, and among these, 44.4% had coinfection. 66.7% and 55.6% of those with high blood pressure and ischemic heart disease, respectively, developed a coinfection. Escherichia coli was the most frequently isolated microorganism.
Conclusions: Females predominated in the series studied, mortality was high, a high percentage of bacterial preparation and comorbidities was evident. More than half of the patients died. Gram-negative bacteria were the microorganisms that were most isolated. Antimicrobial resistance levels were high.
REFERENCES
Madrigal Rojas JP, Quesada Loría M, García Sánchez M, Solano Chinchilla A. SARS CoV-2, manifestaciones clínicas y consideraciones en el abordaje diagnóstico de COVID-19. Revista Médica de Costa Rica. 2020 [acceso: 17/05/2020];85(629):[aprox. 3 p.]. Disponible en: http://www.revistamedicacr.com/index.php/rmcr/article/viewFile/287/264
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020 [acceso: 07/05/2020];395(10223): 507-513. Disponible en: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2820%2930211-7/fulltext#seccestitle150
Kim D, Quinn J, Pinsky B, Shah NH, Brown I. Rates of Co-infection Between SARS-CoV-2 and Other Respiratory Pathogens. JAMA. 2020[acceso: 11/05/2020];323(20):2085-6. Disponible en: http://scholar.google.com/scholar_url?url=https://jamanetwork.-com/journals/jama/articlepdf/2764787/jama_kim_2020_ld_200032.-pdf&hl=es&sa=T&oi=ucasa&ct=ufr&ei=Y9jCXqTAHPiLy9YP8KehmA-o&scisig=AAGBfm2hiKsZ6FMpE4himcrxSVDe56yXmA&nossl=1
Monté Cerero L, Martínez Casanueva R. Microorganismos aislados en pacientes ingresados. Hospital "Salvador Allende", La Habana. Febrero a junio de 2015. Revista Habanera de Ciencias Médicas. 2017 acceso: 07/05/2020;16(4):aprox. 11 p. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/1326
Díaz Medina LM, Medina García M, Duque González AC, Miguélez Nodarse R. Susceptibilidad antimicrobiana en muestras clínicas de pacientes con infecciones asociadas a la atención de salud. Revista Habanera de Ciencias Médicas. 2017 acceso: 07/05/2020;16(3):aprox. 14 p. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/1650
González Castro A, Escudero Acha P, Peñasco Y, Leizaola A, Martínez de Pinillos Sánchez V, García de Lorenzo A. Cuidados intensivos durante la epidemia de coronavirus 2019. Medicina Intensiva. 2020. [acceso: 27/05/2020]. Disponible en: https://www.sciencedirect.com/science/article/pii/S0210569120300899
Acosta G, Escobar G, Bernaola G, Alfaro J, Taype W, Marcos C, et al. Caracterización de pacientes con COVID-19 grave atendidos en un hospital de referencia nacional del Perú. Rev Peru Med Exp Salud Pública. 2020[acceso: 29/05/2020];37(2):253-8. Disponible en: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/5437/3535
Rawson TM, Moore LSP, Zhu N, Ranganathan N, Skolimowska K, Gilchrist M, et al. Bacterial and fungal co-infection in individuals with coronavirus: A rapid review to support COVID-19 antimicrobial prescribing. Clin Infect Dis. 2020[acceso: 26/05/2020]; 0954162(478):1-4. Disponible en: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa530/5828058
Fernández Rodríguez A, Casas I, Culebras E, Morilla E, Cohen MC, Alberola J. COVID-19 y estudios microbiológicos post mortem. Revista Española de Medicina Legal. 2020[acceso: 26/05/2020];46(3):127-38. Disponible en: https://www.sciencedirect.com/science/article/pii/S037747322030030-4/pdf?md5=ec25ee2a89a69b3bd95fae7f52ebbcbe&pid=1-s2.0-S0377473220300304-main.pdf