Ruiz-Alva S, Cortes-Cerda R, Mora-Ríos F, Benítez-Romero A, Isunza-Ramírez A, Mejía-Rohenes L

Language: Spanish
References: 14
Page: 201-205
PDF size: 163.56 Kb.

ABSTRACT

Introduction: A metastasis is the tumor cell capacity to migrate from the primary tumor and implant itself in tissues of an organ at a distance by hematogenous, lymphatic or contiguity. The main causes of bone metastases are: breast, prostate and lung cancer. It usually occurs in patients over 50 years of age. There is a predilection for metastasizing to the axial skeleton. Objective: To determine the frequency of tumors that produce bone metastases in our institution. Material and methods: Observational, cross-sectional, descriptive study, for retrospective analysis of the cases of patients diagnosed with bone metastases. Results: 193 cases; 121 women and 72 men with an age range of 42 to 84 years. Cancers associated with bone metastases were breast, lung, prostate, cervical and renal cancers; to a lesser extent other such as colon, thyroid, liver and skin. The most affected bones were axial skeleton: lumbar and dorsal spine, and in appendicular skeleton the femur in the diaphysiary region and in the humerus the proximal third. At present it has not been possible to improve the effectiveness of timely detection strategies, so bone pain should begin with a protocol of tumor suspicion. Conclusions: More than 80% of the patients came for fracture. All patients had a history of pain greater than 12 months with no prior study protocol.

REFERENCES

1. Contreras CNA, Sosa SR, Green RD. Metástasis óseas de primario desconocido. Médica Sur. 2005; 12(2): 121-8.

2. Moreno CMM, Rodríguez MYM. Rehabilitación del paciente con enfermedad ósea metastásica: un desafío. Rev Col Med Fis Rehab. 2016; 26(1): 95-108.

3. Guzman ESI, Ruiz YVH, Craviotto RAB, Montelongo MEA. Abordaje diagnóstico de la enfermedad ósea metastásica. Rev Sanid Milit Mex. 2015; 69(5): 455-66.

4. Freeman AK, Sumathi VP, Jeys L. Metastatic tumours of bone. Orthopaedics I: General Principles Surgery. 2015; 33(1): 34-9. Available in: doi.org/10.1016/j.mpsur.2014.10.005

5. Takagi T, Katagiri H, Kim Y, Suehara Y, Kubota D, Akaike K, et al. Skeletal metastasis of unknown primary origin at the initial visit: a retrospective analysis of 286 cases. PLoS ONE. 2015; 10(6): 1-17. doi: 10.1371/journal.pone.0129428.

6. Durand JP, Karoubi M, Anract P, Goldwasser F. Metástasis óseas: manejo multidisciplinario, conducta diagnóstica y terapéutica. EMC-Aparatolocomotor. 2013; 46(1): 1-16. Disponible en: doi.org/10.1016/S1286-935X(13)64172-6

7. Hernández-Herrera JM, Hernández-Herrera JJ, Marín-Álvarez A. Revisión bibliográfica del diagnóstico radiológico de las fracturas patológicas. Rev Med Costa Cen. 2012; 59(603): 435-42.

8. Villalobos LML, Villalba YA, Álvarez-Mon SM. Protocolo de manejo clínico de las metástasis óseas. Protocolos de práctica asistencial. Medicine. 2017; 12(33): 1995-9.

9. Octava revisión del Consenso Mexicano sobre Diagnóstico y Tratamiento del Cáncer Mamario de colima 2019.

10. Rosselló ALL, Martín GL, Montalà PN, Conde-Seijas MR, Torres PY, Pallisó FF. Estudio de las características de diferentes cánceres primitivos basado en las metástasis óseas. REEMO. 2008; 17(5): 94-8.

11. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010; 127(12): 2893-917.

12. Reynoso NN, Torres DJA. Epidemiología del cáncer en México: carga global y proyecciones 2000-2020. Revista Latinoamericana de Medicina Conductual. 2017; 8 (1): 9-14.

13. Rodríguez SYM, Ureña GD, Sagaró CNM, Escalona-Fonseca M. Factores pronósticos y supervivencia de mujeres con cáncer de mama en Santiago de Cuba. MEDISAN. 2018; 22(5): 477.

14. Mateo-Alonso M. Epidemiología y factores de riesgo del cáncer pulmonar. Revisión de la literatura. Residente. 2008, 3(1): 15-7.

EVIDENCE LEVEL

IV