2021, Number 10
<< Back Next >>
Ginecol Obstet Mex 2021; 89 (10)
Posterior reversible encephalopathy syndrome secondary to hypertensive disorders of pregnancy. Case series
Osorio-Rodríguez EL, García-Perlaza CJ, Navarro-Devia AJ, Salas-Danies EM, Pineda-Tovar MP, Guevara-Romero E
Language: Spanish
References: 24
Page: 770-778
PDF size: 211.25 Kb.
ABSTRACT
Objective: To describe the clinical and imaging characteristics of patients with posterior
reversible encephalopathy seen in an intensive care unit.
Materials and Methods: Retrospective, descriptive, cross-sectional case series
study performed in patients with a diagnosis of reversible posterior encephalopathy
secondary to hypertensive disorders attended in the intensive care unit of the Hospital
Universitario de la Samaritana, Bogotá, Colombia, between January 1, 2013 and
December 31, 2020.
Resultados: We found 12 patients with reversible posterior encephalopathy; 8 of them with
onset during the immediate puerperium and 4 in the mediate puerperium. Eclampsia
was diagnosed in 6 patients during pregnancy and in 5 during the postpartum period.
The most common symptoms were headache and convulsions. Imaging findings showed
edema most frequently in the posterior lobes of the brain, especially in the bilateral
occipital and parietooccipital lobes. All patients were discharged from the hospital
without irreversible neurological lesions.
Conclusions: Reversible posterior encephalopathy is uncommon but should be
considered in patients with neurologic symptoms concomitant with hypertensive
disorders of pregnancy. Although the sample is small, it can be mentioned that radiological
diagnosis with brain magnetic resonance imaging, timely treatment and
multidisciplinary interventions decrease the risk of irreversible neurological lesions
and fatal outcome.
REFERENCES
Cozzolino M, Bianchi C, Mariani G, Marchi L, et al. Therapy and differential diagnosis of posterior reversible encephalopathy syndrome (PRES) during pregnancy and postpartum. Arch Gynecol Obstet 2015; 292 (6): 1217-23. https://doi. org/10.1007/s00404-015-3800-4.
Katsevman GA, Turner RC, Cheyuo C, Rosen C, et al. Postpartum posterior reversible encephalopathy syndrome requiring decompressive craniectomy: case report and review of the literature. Acta Neurochir (Wien) 2019; 161 (2): 217-24. https://doi.org/10.1007/s00701-019- 03798-4
Demirel I, Kavak BS, Ozer AB, Bayar MK, et al. An intensive care approach to posterior reversible encephalopathy syndrome (PRES): An analysis of 7 cases. J Turkish Ger Gynecol Assoc 2014; 15 (4): 217-21. https://doi.org/10.5152/ jtgga.2014.14072
De la Torre T, Miranda A, Gómez M, Nava J, et al. Encefalopatía posterior reversible durante el puerperio, secundaria a eclampsia. Reporte de dos casos. Ginecol Obstet Mex 2018; 86 (12): 815-22. https://doi.org/10.24245/gom. v86i12.2343
Verhaegen J, Peeters F, Debois P, Jacquemyn Y. Posterior reversible encephalopathy syndrome as a complication of pre-eclampsia in the early postpartum period. BMJ Case Rep 2019; 12 (7): e228954. https://doi.org/10.1136/bcr- 2018-228954
Zambrano MD, Miller EC. Maternal Stroke: an Update. Curr Atheroscler Rep 2019; 21 (9): 33. https://doi.org/10.1007/ s11883-019-0798-2
Tetsuka S, Ogawa T. Posterior reversible encephalopathy syndrome: A review with emphasis on neuroimaging characteristics. J Neurol Sci 2019; 404: 72-9. https://doi. org/10.1016/j.jns.2019.07.018
Marcoccia E, Piccioni MG, Schiavi MC, Colagiovanni V, et al. Postpartum posterior reversible encephalopathy syndrome (PRES): Three case reports and literature review. Case Rep Obstet Gynecol 2019; 2019: 1-11. https://doi. org/10.1155/2019/9527632
Sibai BM. Diagnosis, Controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol 2004; 103 (5, Part 1): 981-91. https://doi.org/10.1097/01.AOG.0000126245.35811.2a
American College of Obstetricians and Gynecologists. Gestational hypertension and preeclampsia. Obstet Gynecol 2020; 135 (6): 1492-5. https://doi.org/10.1097/ AOG.0000000000003892
Stevens PE. Evaluation and management of chronic kidney disease: Synopsis of the kidney disease: improving global outcomes 2012 Clinical Practice Guideline. Ann Intern Med 2013; 158 (11): 825. https://doi.org/10.7326/0003-4819- 158-11-201306040-00007
Singh S, Mohakud S, Naik S, Kumar S, et al. Predictors of posterior reversible encephalopathy syndrome in women with hypertension in pregnancy: A prospective observational study. Pregnancy Hypertens 2021; 23: 191-5. https:// doi.org/10.1016/j.preghy.2020.12.006
Chao AS, Chen YL, Chang YL, Chao A, et al. Severe preeclamptic women with headache: is posterior reversible encephalopathy syndrome an associated concurrent finding? BMC Pregnancy Childbirth 2020; 20 (1): 336. https:// doi.org/10.1186/s12884-020-03017-4
Brewer J, Owens MY, Wallace K, Khan M, et al. Posterior reversible encephalopathy syndrome in 46 of 47 patients with eclampsia. Am J Obstet Gynecol 2013; 208 (6): 468. e1-468.e6. https://doi.org/10.1016/j.ajog.2013.02.015
Rijal JP, Giri S, Dawadi S, Dahal K. Posterior reversible encephalopathy syndrome (PRES) in a patient with late postpartum eclampsia. Case Reports 2014; 2014 (feb27 1): bcr2013203162–bcr2013203162. https://doi.org/10.1136/ bcr-2013-203162
Hossain N, Khan N, Panhwar N, Noureen S. Clinical spectrum of Posterior Reversible Encephalopathy Syndrome (PRES) in patients with eclampsia. Pakistan J Med Sci 2015; 31 (5). https://doi.org/10.12669/pjms.315.7707
Fang X, Wang H, Liu Z, Tan H, et al. Posterior reversible encephalopathy syndrome in preeclampsia and eclampsia: The role of hypomagnesemia. Seizure. 2020; 76: 12-6. https://doi.org/10.1016/j.seizure.2020.01.003
Garg R, Kumar N, Malhotra H. Posterior reversible encephalopathy syndrome in eclampsia. Neurol India 2018; 66 (5): 1316. https://doi.org/10.4103/0028-3886.241364
Sardesai S, Dabade R, Deshmukh S, Patil P, et al. Posterior reversible encephalopathy syndrome (PRES): evolving the mystery of eclampsia. J Obstet Gynecol India 2019; 69 (4): 334-8. https://doi.org/10.1007/s13224-019-01214-6
Konar H, Agarwal L, Priyanka P, Chaudhuri S. Posterior reversible encephalopathy syndrome in women with eclampsia: report of three cases. J Obstet Gynecol India 2021; 71 (3): 318-21. https://doi.org/10.1007/s13224-020-01399-1
Dong X, Nao J. Neurological manifestations, and neuroimaging presentations in patients with severe preeclampsia: predisposing factors and clinical implications. Neurol Sci 2019; 40 (6): 1245-53. https://doi.org/10.1007/s10072- 019-03833-3
Junewar V, Verma R, Sankhwar PL, Garg R. Neuroimaging features and predictors of outcome in eclamptic encephalopathy: A prospective observational study. Am J Neuroradiol 2014; 35 (9): 1728-34. https://doi.org/10.3174/ajnr.A3923
Fisher N, Saraf S, Egbert N, Homel P, et al. Clinical correlates of posterior reversible encephalopathy syndrome in pregnancy. J Clin Hypertens 2016; 18 (6): 522-7. https:// doi.org/10.1111/jch.12656
Mayama M, Uno K, Tano S, Kishigami Y, et al. Incidence of posterior reversible encephalopathy syndrome in eclamptic and patients with preeclampsia with neurologic symptoms. Am J Obstet Gynecol 2016; 215 (2): 239.e1-239.e5. https:// doi.org/10.1016/j.ajog.2016.02.039