2021, Number 10
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Ginecol Obstet Mex 2021; 89 (10)
COVID-19 and pregnancy: report of 15 cases
Zárate-Jesús M, González-Rangel G, Montes-Casillas YE, Fimbres-García G
Language: Spanish
References: 29
Page: 753-759
PDF size: 180.95 Kb.
ABSTRACT
Objective: To describe the clinical characteristics of pregnancy, biochemical alterations
and obstetric outcomes of patients with positive COVID-19 test.
Materials and Methods: Observational, case series, analytical, retrospective, and
cross-sectional study performed by reviewing clinical records of pregnant patients with
confirmed clinical picture (by PCR for SARS-CoV-2) of COVID-19.
Results: Fifteen cases of patients with positive test for SARS-CoV-2 were studied.
The mean age was 28.67 years (SD ± 6.11); 14 of the 15 were in the third trimester of
pregnancy, 11 of 15 had mild disease. Pregnancy was terminated by cesarean section
in 12 of 15 patients and 3 of 15 required specialized care by specialists in critical
care medicine.
Conclusions: The clinical features and severity of the disease appear to be similar
in pregnant and non-pregnant patients. The main reason for hospitalization and termination
of pregnancy was due to obstetric causes.
REFERENCES
Elwood C, Raeside A, Watson H, Boucoiran I, Money D, Yudin M, et al. Committee Opinion No. 400: COVID-19 and Pregnancy [Internet]. 2021 feb. https://sogc.org/common/ Uploaded%20files/Latest%20News/Committee%20Opinion% 20No.%20400%20COVID-19%20and%20Pregnancy.pdf
Wastnedge EAN, Reynolds RM, van Boeckel SR, Stock SJ, Denison FC, Maybin JA, et al. Pregnancy and COVID-19. Physiol Rev 2021; 101 (1): 303-18. doi: 10.1152/physrev. 00024.2020
Centro Nacional de Equidad de Género y Salud Reproductiva. Lineamiento para la prevención y mitigación de COVID-19 en la atención del embarazo, parto, puerperio y de la persona recién nacida. México: Gobierno del Estado, 2020. https://www.gob.mx/cms/uploads/attachment/ file/546239/Lineamiento_prevencion_y_mitigacion_de_ COVID-19_en_el_embarazo_CNEGSR__1_.pdf
La Cour Freiesleben N, Egerup P, Hviid KVR, Severinsen ER, Kolte AM, et al. SARS-CoV-2 in first trimester pregnancy: a cohort study. Hum Reprod 2021; 36 (1): 40-47. doi: 10.1093/humrep/deaa311
D'Souza R, Ashraf R, Rowe H, Zipursky J, Clarfield L, et al. Pregnancy and COVID-19: pharmacologic considerations. Ultrasound Obstet Gynecol 2021; 57 (2): 195-203. doi: 10.1002/uog.23116
World Health Organization. COVID-19 Weekly Epidemiological Update. 2021 jun. https://www.who.int/ publications/m/item/weekly-epidemiological-update-oncovid- 19---1-june-2021
Dirección General de Epidemiologia. Lineamiento Estandarizado para la Vigilancia Epidemiológica y por Laboratorio de la Enfermedad Respiratoria Viral. Secretaria de Salud. Abril 2020. https://coronavirus.gob.mx/wp-content/ uploads/2020/04/Lineamiento_de_vigilancia_epidemiologica_ de_enfermedad_respiratoria-_viral.pdf
Salem D, Katranji F, Bakdash T. COVID-19 infection in pregnant women: Review of maternal and fetal outcomes. Int J Gynaecol Obstet 2021; 152 (3): 291-298. doi: 10.1002/ ijgo.13533
Rotshenker-Olshinka K, Volodarsky-Perel A, Steiner N, Rubenfeld E, Dahan MH. COVID-19 pandemic effect on early pregnancy: are miscarriage rates altered, in asymptomatic women? Arch Gynecol Obstet 2021; 303 (3): 839-845. doi: 10.1007/s00404-020-05848-0
Zhou J, Wang Y, Zhao J, Gu L, Yang C, et al. The metabolic and immunological characteristics of pregnant women with COVID-19 and their neonates. Eur J Clin Microbiol Infect Dis 2021; 40 (3): 565-74. doi: 10.1007/s10096-020-04033-0
Royal College of Obstetricians & Gynaecologists. Coronavirus (COVID-19) Infection in Pregnancy. Information for healthcare professionals. Versión 13. 2021 feb. https://www.rcog.org.uk/globalassets/documents/ guidelines/2021-02-19-coronavirus-covid-19-infectionin- pregnancy-v13.pdf
Poon LC, Yang H, Dumont S, Lee JCS, Copel JA, Danneels L, et al. ISUOG Interim Guidance on coronavirus disease 2019 (COVID-19) during pregnancy and puerperium: information for healthcare professionals. Ultrasound Obstet Gynecol 2020; 55: 848-62 https://doi.org/10.1002/uog.22061
Du M, Yang J, Han N, Liu M, Liu J. Association between the COVID-19 pandemic and the risk for adverse pregnancy outcomes: a cohort study. BMJ Open 2021; 11 (2): e047900. doi: 10.1136/bmjopen-2020-047900
Moore KM, Suthar MS. Comprehensive analysis of COVID- 19 during pregnancy. Biochem Biophys Res Commun 2021; 538: 180-86. doi: 10.1016/j.bbrc.2020.12.064
Centre de Medicina Fetal i Neonatal de Barcelona. Protocolo: coronavirus (Covid-19) y gestación (v8 - 30/05/2020). España: Clinic Barcelona, 2020.https://medicinafetalbarcelona. org/protocolos/es/patologia-materna-obstetrica/ covid19-embarazo.pdf
Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC. Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound Obstet Gynecol 2020; 56: 15-27 https://doi.org/10.1002/uog.22088
MS THM, Vaught J, and the SMFM COVID-19 Task Force. Management Considerations for Pregnant Patients With COVID-19. 2021 feb. https://s3.amazonaws.com/cdn. smfm.org/media/2734/SMFM_COVID_Management_of_ COVID_pos_preg_patients_2-2-21_(final).pdf
National Institutes of Health. COVID-19 Treatment Guidelines Panel, coronavirus Disease 2019 (COVID-19) treatment guidelines. NIH; 2020. https://files.covid19treatmentguidelines. nih.gov/guidelines/covid19treatmentguidelines.pdf
Di Toro F, Gjoka M, Di Lorenzo G, De Santo D, De Seta F, et al. Impact of COVID-19 on maternal and neonatal outcomes: a systematic review and meta-analysis. Clin Microbiol Infect 2021; 27 (1): 36-46. doi: 10.1016/j.cmi.2020.10.007
Cavalcante MB, Cavalcante CTMB, Sarno M, Barini R, Kwak-Kim J. Maternal immune responses and obstetrical outcomes of pregnant women with COVID-19 and possible health risks of offspring. J Reprod Immunol 2021; 143: 103250. doi: 10.1016/j.jri.2020.103250
Oshay RR, Chen MYC, Fields BKK, Demirjian NL, Lee RS, Mosallaei D, Gholamrezanezhad A. COVID-19 in pregnancy: a systematic review of chest CT findings and associated clinical features in 427 patients. Clin Imaging 2021; 75:75- 82. doi: 10.1016/j.clinimag.2021.01.004
Matar R, Alrahmani L, Monzer N, Debiane LG, Berbari E, Fares J, Fitzpatrick F, Murad MH. Clinical Presentation and Outcomes of Pregnant Women with Coronavirus Disease 2019: A Systematic Review and Meta-analysis. Clin Infect Dis 2021; 72 (3): 521-33. doi: 10.1093/cid/ciaa828
Dirección General de Epidemiologia. Recomendaciones para el tratamiento de la infección por SARS-CoV-2, agente causal de COVID-19. México: Secretaria de Salud; 2020. https://coronavirus.gob.mx/wp-content/ uploads/2020/07/Recomendaciones_para_tratamiento_ SARS-CoV2.pdf
Barrantes JH, Ortoleva J, O'Neil ER, Suarez EE, Beth Larson S, et al. Successful Treatment of Pregnant and Postpartum Women with Severe COVID-19 Associated Acute Respiratory Distress Syndrome With Extracorporeal Membrane Oxygenation. ASAIO J 2021; 67 (2): 132-36. doi: 10.1097/ MAT.0000000000001357
Lopian M, Kashani-Ligumsky L, Czeiger S, Cohen R, Schindler Y, et al. Safety of vaginal delivery in women infected with COVID-19. Pediatr Neonatol 2021; 62 (1): 90-96. doi: 10.1016/j.pedneo.2020.10.010
Wang CL, Liu YY, Wu CH, Wang CY, Wang CH, Long CY. Impact of COVID-19 on Pregnancy. Int J Med Sci 2021; 18 (3): 763-67. doi: 10.7150/ijms.49923
Halscott T, Vaught J, Miller E. Management considerations for pregnant patients with COVID-19. EEUU: Society for Maternal-Fetal Medicine, 2020. https://s3.amazonaws. com/cdn.smfm.org/media/2415/SMFM_COVID_Management_ of_COVID_pos_preg_patients_7-2-20.PDF_.pdf
Benhamou D, Keita H, Ducloy-Bouthors AS; Obstetric Anaesthesia and Critical Care Club Working Group. Coagulation changes and thromboembolic risk in COVID-19 obstetric patients. Anaesth Crit Care Pain Med 2020; 39 (3): 351-53. doi: 10.1016/j.accpm.2020.05.003
Guasch E, Brogly N, Manrique S. Practical recommendations in the obstetrical patient with a COVID-19 infection. Rev Esp Anestesiol Reanim 2020; 67 (8): 438-45. doi: 10.1016/j.redar.2020.06.009