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2000, Number 1

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Rev Mex Patol Clin Med Lab 2000; 47 (1)

Chlamydia pneumoniae seropositivity and its association with cardiovascular disease

Sánchez-González J, Moragrega AJL, Rivera CAE, Gil CF, Andrade QM

Language: Spanish
References: 38
Page: 4-12
PDF size: 147.82 Kb.


ABSTRACT

Introduction: Chlamydia pneumoniae it is a bacteria with a contact prevalence in but of the world population’s 80% and associated with cardiovascular disease (ECV) and atherosclerosis. In Mexico they are scarce the studies and not conclusive in the demonstration of this association.
Objective: The purpose of the present study was to identify the frequency from the exhibition to Ch. pneumoniae in patient with ECV, as well as to establish the influence of the gender and the age in the expression of this relationship.
Material and methods: 30 individuals of both sexes were studied with acute and chronic ECV, assigned to two groups. The group I, integrated by 12 patients with antecedents of stable ECV and the group II, formed by 18 patients with presence acute ECV, with serum determinations of antibodies levels of IgG and IgA vs Ch. pneumoniae. Results: The general serumpositivity was of 40%; nine of the 18 patients of the group II (50%) and three of the 12 patients of the group I (25%) they presented positivity (bigger at 1:16). The probability of presenting the exhibition to Ch. pneumoniae was bigger in the group with acute disease and in a proportion 2 times superior (25% vs 50%; p‹ 0.05), and the occurrence probability was bigger among the males than among the women (70% vs 30%; p ‹ 0.05).
Conclusions: The obtained data of the study corroborate a high exhibition prevalence to Ch. pneumoniae in patient with acute cardiovascular events. They indicate a marked tendency of the association in males, independently of the age.


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