Pérez-Armendáriz LÁ, Nava-Hernández MP, Amador-Robles M, Rosales-González M, Meza-Velázquez R

Language: Spanish
References: 17
Page: 54-57
PDF size: 150.94 Kb.

ABSTRACT

Adverse reactions related to food allergy are IgE-mediated, mixed or cell-mediated and, as a result, there are disorders that affect several target organs (skin, intestine, respiratory tract and cardiovascular system) at different age stages, with specific diagnoses for each of the pathologies. The IgE-mediated mechanism is considered the classic mark of an allergic reaction; on the other hand, those mechanisms that are not mediated by IgE are considered non-allergic hypersensitivity, and are related to cells or other types of immunoglobulins. Cellular responses have been described involving CD4 and CD8 T lymphocytes specific to the food antigen, as well as cells of the innate immune response such as neutrophils. The objective of this review is to present the different pathophysiologies in the mechanisms involved in unfavorable reactions to food, and thus propose a therapeutic target according to the mechanism involved in the immunopathology.

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