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2020, Number 2

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Rev Cubana Med Gen Integr 2020; 36 (2)

Prevalence of frailty syndrome and associated factors in elderly adults

Herrera-Perez D, Soriano-Moreno AN, Rodrigo-Gallardo PK, Toro-Huamanchumo CJ

Language: Spanish
References: 45
Page: 1-17
PDF size: 629.37 Kb.


ABSTRACT

Introduction: In Latin America, the prevalence of frailty syndrome in non-institutionalized elderly adults aged 60 years and older ranges from 7.7 to 39.3%. In Peru, few studies have addressed this topic and its associated factors in similar populations.
Objective: To identify the prevalence of frailty and the associated factors in elderly adults from seven primary care centers.
Methods: Analytical and cross-sectional study whose outcome variable was the presence of frailty, according to the Fried criteria. We also included sociodemographic data (for occupation, the classifications of the Spanish Society of Epidemiology [SEE in Spanish] and the Spanish Society of Family and Community Medicine [SEMFyC in Spanish] were used), depression screening (using the Yesavage scale), degree of functionality (using the Barthel index), and comorbidities (using the Geriatric Index of Comorbidity and Greenfield’s severity index).
Results: 116 older adults were evaluated. The prevalence of frailty was 20.7%. The associated factors were having two or more illnesses (RPa=3.33; 95% CI: 1.04-10.68), having moderate depression (RPa=6.50; 95% CI: 2.52-16.75), and moderate dependence for performing daily-life activities (RPa=2.63; 95% CI: 2.63-14.15). Protective factors were having had a class III occupation (RPa=0.11; 95% CI: 0.02-0.54), class IV (RPa=0.07; 95% CI: 0.01-0.35), or class V (RPa=0.24; 95% CI: 0.09-0.60), and living with a relative (RPa=0.25; 95% CI: 0.08-0.74).
Conclusion: One in five elderly adults was frail. Depressive symptoms, having two or more comorbidities, and being dependent for daily-life activities were factors associated with frailty. On the other hand, working in non-managerial positions and living with a family member were protective factors.


REFERENCES

  1. Alvarado García AM, Salazar Maya ÁM. Análisis del concepto de envejecimiento. Gerokomos. 2014;25(2):57-62.

  2. Centers for Disease Control and Prevention (CDC). Trends in aging--United States and worldwide. MMWR Morb Mortal Wkly Rep. 2003;52(6):101-6.

  3. Manini T. Development of physical disability in older adults. Curr Aging Sci. 2011;4(3):184-91.

  4. Marengoni A, Rizzuto D, Wang HX, Winblad B, Fratiglioni L. Patterns of chronic multimorbidity in the elderly population. J Am Geriatr Soc. 2009;57(2):225-30.

  5. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146-156.

  6. Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the Concepts of Disability, Frailty, and Comorbidity: Implications for Improved Targeting and Care. J Gerontol A Biol Sci Med Sci. 2004;59(3):M255-63.

  7. Varela-Pinedo L, Ortiz-Saavedra PJ, Chávez-Jimeno H. Síndrome de fragilidad en adultos mayores de la comunidad de Lima Metropolitana. Rev Soc Peru Med Interna. 2008;21(1):11-5.

  8. Samper-Ternent R, Reyes-Ortiz C, Ottenbacher KJ, Cano CA. Frailty and sarcopenia in Bogotá: results from the SABE Bogotá Study. Aging Clin Exp Res. 2017;29(2):265-72.

  9. Sánchez-García S, García-Peña C, Salvà A, Sánchez-Arenas R, Granados-García V, Cuadros-Moreno J, et al. Frailty in community-dwelling older adults: association with adverse outcomes. Clin Interv Aging. 2017;12:1003-11.

  10. Gonzáles-Mechán MC, Leguía-Cerna J, Díaz-Vélez C. Prevalencia y factores asociados al síndrome de fragilidad en adultos mayores en la consulta de atención primaria de EsSalud, enero-abril 2015. Chiclayo, Perú. Horizonte Médico. 2017;17(3):35-42.

  11. Runzer-Colmenares FM, Samper-Ternent R, Al Snih S, Ottenbacher KJ, Parodi JF, Wong R. Prevalence and factors associated with frailty among Peruvian older adults. Arch Gerontol Geriatr. 2014;58(1):69-73.

  12. Fhon JRS, Rosset I, Freitas CP, Silva AO, Santos JLF, Rodrigues RAP, et al. Prevalence of falls among frail elderly adults. Revista de Saúde Pública. 2013;47(2):266-73.

  13. Ferreira D, Salles F, Golino C, Rodrigues B. Frailty of Elderly Residents in a Municipality with a High Human Development Index: Vitória, Southeastern, Brazil. Journal of Pain and Symptom Management. 2018;56(6):e73.

  14. Andrade JM, Duarte YA de O, Alves LC, Andrade FCD, Souza Junior PRB de, Lima-Costa MF, et al. Frailty profile in Brazilian older adults: ELSI-Brazil. Rev Saude Publica. 2018;52Suppl 2(Suppl 2):17s.

  15. Da Silva VD, Tribess S, Meneguci J, Sasaki JE, Santos D de AT, Carneiro JAO, et al. Time Spent in Sedentary Behaviour as Discriminant Criterion for Frailty in Older Adults. Int J Environ Res Public Health. 2018;15(7):E1336.

  16. Alcalde-Rabanal JE, Lazo-González O, Nigenda G. Sistema de salud de Perú. Salud pública Méx. 2011;53:s243-54.

  17. Ng TP, Feng L, Nyunt MSZ, Feng L, Niti M, Tan BY, et al. Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial. Am J Med. 2015;128(11):1225-1236.e1.

  18. Sánchez-Moreno F. La inequidad en salud afecta el desarrollo en el Perú. Revista Peruana de Medicina Experimental y Salud Publica. 2013;30(4):676-82.

  19. Grupo de trabajo de la Sociedad Española de Epidemiología y de la Sociedad Española de Medicina de Familia y Comunitaria. Una propuesta de medida de la clase social. Aten Primaria. 2000;25(5):350-63.

  20. Jürschik Giménez P, Escobar Bravo MÁ, Nuin Orrio C, Botigué Satorra T. Criterios de fragilidad del adulto mayor. Estudio piloto. Atención Primaria. 2011;43(4):190-6.

  21. Abizanda-Soler P, Rodríguez-Mañas L. Tratado de medicina geriátrica. Fundamentos de la atención sanitaria a los mayores. Elsevier; 2014.

  22. Martínez de la Iglesia J, Onís Vilches MC, Dueñas Herrero R, Albert Colomer C, Aguado Taberné C, Luque Luque R. The Spanish version of the Yesavage abbreviated questionnaire (GDS) to screen depressive dysfunctions in patients older than 65 years. Medifam. 2002;12(10):26-40.

  23. Juarez J, Leon A, Alata-Linares V. Evaluación del grado de depresión de adultos mayores de 60 años del AA.HH "Viña alta" - La Molina, Lima-Perú. Horiz Med. 2012;12(2):28-31.

  24. Cid-Ruzafa J, Damián-Moreno J. Valoración de la discapacidad física: el indice de Barthel. Revista Española de Salud Pública. 1997;71(2):127-37.

  25. González N, Bilbao A, Forjaz MJ, Ayala A, Orive M, Garcia-Gutierrez S, et al. Psychometric characteristics of the Spanish version of the Barthel Index. Aging Clin Exp Res. 2018;30(5):489-97.

  26. Rosas-Carrasco O, Gonzalez-Flores E, Brito-Carrera AM, Vazquez-Valdez OE, Peschard-Saenz E, Gutierrez-Robledo LM, et al. Evaluación de la comorbilidad en el adulto mayor. Rev Med Inst Mex Seguro Soc. 2011;49(2):153-162.

  27. Rozzini R, Frisoni GB, Ferrucci L, Barbisoni P, Sabatini T, Ranieri P, et al. Geriatric Index of Comorbidity: validation and comparison with other measures of comorbidity. Age Ageing. 2002;31(4):277-85.

  28. Siriwardhana DD, Hardoon S, Rait G, Weerasinghe MC, Walters KR. Prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries: a systematic review and meta-analysis. BMJ Open. 2018;8(3):e018195.

  29. Tello-Rodríguez T, Varela-Pinedo L. Fragilidad en el adulto mayor: detección, intervención en la comunidad y toma de decisiones en el manejo de enfermedades crónicas. Rev Peru Med Exp Salud Pública. 2016;33(2):328-34.

  30. Alvarado BE, Zunzunegui MV, Béland F, Bamvita JM. Life course social and health conditions linked to frailty in Latin American older men and women. J Gerontol A Biol Sci Med Sci. 2008;63(12):1399-406.

  31. Jürschik P, Nunin C, Botigué T, Escobar MA, Lavedán A, Viladrosa M. Prevalence of frailty and factors associated with frailty in the elderly population of Lleida, Spain: the FRALLE survey. Arch Gerontol Geriatr. 2012;55(3):625-31.

  32. Soysal P, Veronese N, Thompson T, Kahl KG, Fernandes BS, Prina AM, et al. Relationship between depression and frailty in older adults: A systematic review and meta-analysis. Ageing Res Rev. 2017;36:78-87.

  33. Soysal P, Stubbs B, Lucato P, Luchini C, Solmi M, Peluso R, et al. Inflammation and frailty in the elderly: A systematic review and meta-analysis. Ageing Res Rev. 2016;31:1-8.

  34. Soysal P, Isik AT, Carvalho AF, Fernandes BS, Solmi M, Schofield P, et al. Oxidative stress and frailty: A systematic review and synthesis of the best evidence. Maturitas. 2017;99:66-72.

  35. Black CN, Bot M, Scheffer PG, Cuijpers P, Penninx BWJH. Is depression associated with increased oxidative stress? A systematic review and meta-analysis. Psychoneuroendocrinology. 2015;51:164-75.

  36. Lakey SL, LaCroix AZ, Gray SL, Borson S, Williams CD, Calhoun D, et al. Antidepressant use, depressive symptoms, and incident frailty in women aged 65 and older from the Women's Health Initiative Observational Study. J Am Geriatr Soc. 2012;60(5):854-61.

  37. Al Snih S, Graham JE, Ray LA, Samper-Ternent R, Markides KS, Ottenbacher KJ. Frailty and incidence of activities of daily living disability among older Mexican Americans. J Rehabil Med. 2009;41(11):892-7.

  38. Provencher V, Béland F, Demers L, Desrosiers J, Bier N, Ávila-Funes JA, et al. Are frailty components associated with disability in specific activities of daily living in community-dwelling older adults? A multicenter Canadian study. Arch Gerontol Geriatr. 2017;73:187-94.

  39. Iavicoli I, Leso V, Cesari M. The contribution of occupational factors on frailty. Arch Gerontol Geriatr. 2018;75:51-8.

  40. Herrera-Badilla A, Navarrete-Reyes AP, Amieva H, Avila-Funes JA. Loneliness is associated with frailty in community-dwelling elderly adults. J Am Geriatr Soc. 2015;63(3):607-9.

  41. Walston J, McBurnie MA, Newman A, Tracy RP, Kop WJ, Hirsch CH, et al. Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med. 2002;162(20):2333-41.

  42. Jaremka LM, Fagundes CP, Peng J, Bennett JM, Glaser R, Malarkey WB, et al. Loneliness promotes inflammation during acute stress. Psychol Sci. 2013;24(7):1089-97.

  43. Foreman KJ, Marquez N, Dolgert A, Fukutaki K, Fullman N, McGaughey M, et al. Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016-40 for 195 countries and territories. Lancet. 2018;392(10159):2052-90.

  44. Varela L, Chávez H, Herrera A, Ortiz P, Chigne O. Valoración geriátrica integral en adultos mayores hospitalizados a nivel nacional. Diagnóstico. 2004;43:57-63.

  45. Starfield B, Shi L, Macinko J. Contribution of primary care to health systems and health. Milbank Q. 2005;83(3):457-502.




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