Medina ML, MacRae K, Toffoli L, Sampayo T, Freschi S

Language: Spanish
References: 26
Page: 97-101
PDF size: 201.66 Kb.

ABSTRACT

sars-cov-2 infections appear to affect children less frequently and severely than adults. Children are frequently asymptomatic or have less severe symptoms and, therefore, less tested.
Objective. To determine prevalence and epidemiological characterization of sars-cov-2 in children from Chaco, Argentina.
Material and method. Descriptive, observational study. Once authorized by the Ethics Committee, the Chaco Epidemiology Computerized Database was reviewed, laboratory confirmed pediatric patients with sars-cov-2 infection of both sexes were included, aged between 30 days of life and under 13 years and 11 months of age, from March to September 2020.
Results. 320 pediatric patients (170 men and 150 women) were admitted. The ages between one and 13 years; average of seven years. The provenance mostly from Resistencia. Regarding morbidities, 86.8% did not present any type and 13.1% did. The most frequent comorbidity was asthma. Regarding the signs and symptoms of presentation: 285 (89%) presented signs-symptoms and 35 (10.9%) asymptomatic. The most frequent signs and symptoms were: fever 106 (37.1%); cough 61 (21.4%); odynophagia 47 (16.4%).
Conclusions. In the studied population, a higher prevalence of symptomatic was found; being fever and cough, the most prevalent symptoms, however they cannot be considered characteristic of sars-cov-2 in children, requiring further studies.

REFERENCES

1. Márquez Aguirre, M.P., Gutiérrez Hernández, A., Lizárraga López, S.L., Muñoz Ramírez, C.M., Ventura Gómez, S.T., Zárate Castañón, P.M. et al., “Espectro clínico de covid-19, enfermedad en el paciente pediátrico”, Acta Pediatr Mex, 2020, 41 (1): s64-s71.

2. Zimmermann, P. y Curtis, N., “Coronavirus infections in children including covid-19 an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children”, Pediatr Infect Dis J, 2020, 39: 355-368.

3. Bi, Q., Wu, Y., Mei, S., Ye, Ch., Zou, X., Zhang, Z. et al., “Epidemiology and transmission of covid-19 in Shen zhen China: analysis of 391 cases and 1 286 of their close contacts”, medRxiv, 2020, 1-22.

4. Guan, W.J., Ni, Z.Y., Hu, Y., Liang, W.H., Ou, C.Q., He, J.X. et al., “Clinical characteristics of coronavirus disease 2019 in China”, N Engl J Med, 2020, 382: 1708- 1720.

5. Chen, H., Guo, J., Wang, C., Lua, F., Yu, X., Zhang, W. et al., “Clinical characteristics and intrauterine vertical transmission potential of covid-19 infection in nine pregnant women: a retrospective review of medical records”, The Lancet, 2020: 1-7.

6. Calvo, C., Tagarro, A., Otheo, E., Epalza, C. y Grupo de Seguimiento de la Infección por sars-cov-2 en la Comunidad de Madrid, “Actualización de la situación epidemiológica de la infección por sars-cov-2 en España: comentarios a las recomendaciones de manejo de la infección en pediatría”, Cartas científicas, 2020, 92 (4): 239-240.

7. Rojas Silva, O., Pavón Rojas, A., Cisnero Reyes, L. y Escalona González, S.O., “Aspectos generales de la covid-19 en pacientes pediátricos”, Rev Cub Med Mil, 2020, 49 (3): e877.

8. Dong, Y., Mo, X., Hu, Y., Qi, X., Jiang, F., Jiang, Z. et al., “Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China”, J Pediatr, 2020.

9. Zhang, B., Liu, S., Zhang, J., Xiao, J., Zhu, S., Dong, Y. et al., “Children hospitalized for coronavirus disease 2019 (covid-19): a multicenter retrospective descriptive study”, J Infect, 2020, 81 (2): e74-75.

10. Domínguez Rojas, J., Estupiñán Vigil, M., Garcés-Ghilardi, R., Alvarado-Gamarra, G., Del Águila, O., Lope Tenorio, A.F. et al., “Estudio transversal analítico de las características y desenlaces clínicos de niños hospitalizados con covid-19 en Lima, Perú”, Medwave, 2021, 21 (1): e8107.

11. Palazzi Safadi, M.A., “The intriguing features of covid-19 in children and its impact on the pandemic”, J Pediatr, 2020, 96 (3): 265-268.

12. Núñez Paucar, H., Candela Herrera, J.L., Aranda Paniora, F., Huby Muñoz, C.L., De Coll Vela, L.E. y Bernal Mancilla, R.R., “Características clínicas, de laboratorio y radiológicas de pacientes pediátricos hospitalizados con covid-19: serie de casos”, Rev Peru Med Exp Salud Pública, 2020, 37 (4): 767-772.

13. Parri, N., Lenge, M. y Buonsenso, D., “Coronavirus Infection in Pediatric Emergency Departments (Confidence) Research Group. Children with covid-19 in Pediatric Emergency Departments in Italy”, N Engl J Med, 2020, 383 (2): 187-190.

14. Han, Q., Lin, Q., Jin, S. y You, L., “Coronavirus 2019-ncov: a brief perspective from the front line”, J Infect, 2020, 80 (4): 373-377.

15. Hellewell, J., Abbott, S., Gimma, A., Bosse, N.I., Jarvis, C.I., Russell, T.W. et al., “Feasibility of controlling covid-19 outbreaks by isolation of cases and contacts”, Lancet Glob Health, 2020, 8 (4): 88-96.

16. Lai, C.C., Shih, T.P., Ko, W.C., Tang, H.J. y Hsueh, P.R., “Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) and coronavirus disease-2019 (covid-19): the epidemic and the challenges”, Int J Antimicrob Agents, 2020, 55 (3): 1-9.

17. Liu, W., “Detection of covid-19 in children in early January 2020 in Wuhan, China”, nejm, 2020, 382: 14.

18. Rothan, H.A. y Byrareddy, S.N., “The epidemiology and pathogenesis of coronavirus disease (covid-19) outbreak”, J Autoimmun, 2020, 109: 102433.

19. Qiu, H., Wu, J., Hong, L., Luo, Y., Song, Q. y Chen, D., “Clinical and epidemiological features of 36 children with coronavirus disease 2019 (covid-19) in Zhejiang, China: an observational cohort study”, The Lancet, 2020, 20: 689:696.

20. Díaz Colina, J.A., Interian Morales, M.T., López Hernández, I.C., Yanes Morales, C.D. y Peregrín Baquero, D., “Aspectos clínico-epidemiológicos en 36 niños cubanos con covid-19”, Revista Cubana de Pediatría, 2020, 92 (1): e1261.

21. Wu, Z. y McGoogan, J.M., “Characteristics of 2019 an important lesson from the coronavirus disease (covid- 19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention”, jama, 2020, 323 (13): 1239-1242.

22. Calvo, C., García López, Hortelano, M., Carlos Vicente, J.C. y Vázquez Martínez, J.L., “Recomendaciones sobre el manejo clínico de la infección por el ‘nuevo coronavirus’ sars-cov-2. Grupo de trabajo de la Asociación Española de Pediatría (aep)”, An Pediatr (Barcelona), 2020, 92 (4): 241.e1-241.e11.

23. Cai, J.H., Wang, X.S., Ge, Y.L., Xia, A.M., Chang, H.L., Tian, H. et al., “First case of 2019 novel coronavirus infection in children in Shanghai”, Zhonghua Er Ke Za Zhi, 2020, 58: e002.

24. Morilla, L., Morel, Z. y Pavlicich, V., “Características clínicas de los pacientes pediátricos con covid-19 en un departamento de emergencia”, Pediatr (Asunción), 2020, 47 (3):124-131.

25. Shekerdemian, L.S., Mahmood, N.R., Wolfe, K.K., Riggs, B.J., Ross, C.E., McKiernan, C.A., Heidemann, S.M., Kleinman, L.C., Sen, A.I., Hall, M.W., Priestley, M.A., McGuire, J.K., Boukas, K., Sharron, M.P., Burns, J.P., International covid-19 picu Collaborative et al., “Characteristics and outcomes of children with coronavirus disease 2019 (covid-19) infection admitted to US and Canadian pediatric intensive care units”, jama Pediatr, 2020, 1174 (9): 868-873.

26. Márquez Aguirre, M.P., Gutiérrez Hernández, A., Lizárraga López, S.L., Muñoz Ramírez, C.L., Ventura Gómez, S.T., Zárate Castañón, P.M., González Mercado, L.A. et al., “Espectro clínico de covid-19, enfermedad en el paciente pediátrico”, Acta Pediatr Mex, 2020, 41 (1): s64-s71.