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2021, Number 4

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Med Crit 2021; 35 (4)

Lung protective ventilation, mechanical power, driving pressure and its relation to mortality and SOFA in patients with invasive mechanical ventilation

Rodríguez MSJI, Castro MHH, Oyarvide ZAK, Flores OGA

Language: Spanish
References: 31
Page: 186-193
PDF size: 226.03 Kb.


ABSTRACT

Introduction: Mechanical ventilation is the cornerstone of the treatment of patients with acute respiratory failure, however, it is not free of complications and eventual adverse events. Objective: To describe the relationship between EVPP, PM and PDP with mortality and SOFA in adult patients with IMV attended at HGZ No. 11, IMSS, Piedras Negras, Coahuila. Material and methods: Prospective, observational study, September 2019 to March 2020 of adult patients with invasive mechanical ventilation. The independent variable was LPV, MP and DP. The dependent variables were mortality and SOFA. Results: 63 patients were enrolled. Main characteristics: age 55 years female 44.4%, location: ward 50.8%, ER 17.5% and ICU 31.8%. Diagnoses: sepsis 20.6%, severe TBI 7.8%, stroke 7.8%, CAP 6.4% and others 57.4%. Hospital mortality 77.8%. Factors associated with mortality: age OR 1.09 (p = 0.01) and plateau pressure OR 1.3 (p = 0.03); DP OR 1.4 (p = 0.12), MP OR 0.79 (p = 0.07) and LPV OR 1.5 (p = 0.7). Factors associated with SOFA: SAPS 3 (r) = 0.53 p < 0.0001. SMR 1.06 95% CI 0.80-1.4 p = 0.63. Conclusions: LPV, DP and MP were not related to mortality or SOFA in this cohort of patients.


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