Pereira MFAC, Rangel FBDH, de Souza CCF

Language: Spanish
References: 26
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ABSTRACT

Introduction: The genus Bauhinia is made up of more than 300 plants worldwide. Several of its species have shown antifungal activity.
Objective: To evaluate the chemical profile of the essential oil of the Bauhinia rufa (Bong.) Steud flower from four regions of Goiás, Brazil, to determine its antifungal activity against Candida isolates.
Methods: Essential-oil extraction from the Bauhinia rufa flower was carried out using a Clevenger-type system. The yield was determined by the mass difference and relative density in pycnometer. The chemical profile was evaluated by gas chromatography/mass spectrometer, and the antifungal activity was determined at different essential oil concentrations using the disk diffusion method. The Tukey test was performed for statistically significant difference (p<0.05).
Results: The essential oil yield was 0.067%; 0.045%; 0.098%, and 0.065%, with densities of 0.907 g mL-1; 0.905 g mL-1; 0.908 g mL-1 and 0.904 g mL-1, respectively for the regions of Rio Verde, Jataí, Caiapônia, and Pilar de Goiás. The chemical profile showed the presence of 39 compounds: six with the highest percentage of β-pinene, trans-verbenol, elemol, globulol, viridiflorol and oplopanone. Antifungal activity against the genus Candida was satisfactory against all the isolates tested.
Conclusions: The essential oil of the Bauhinia rufa (Bong.) Steud flower shows good content of essential oil. The evaluation outcomes of its antifungal activity evaluation against the Candida strains analyzed place it as a possible candidate to develop a new antifungal.

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