2000, Number 6
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Rev Fac Med UNAM 2000; 43 (6)
Hepatic failure in the pathogenesis of SIRS
Rodríguez MCM
Language: Spanish
References: 20
Page: 226-229
PDF size: 38.14 Kb.
ABSTRACT
The systemic inflammatory response syndrome is a generalized inflammatory process secondary to sepsis or other noninfectious conditions such as pancreatitis, haemorrhagic shock, ischemia or others. It is related with the body’s capacity to react to those aggressions, the immunologic response and other protective factors.
Studies on rats and dogs have found a diminished hepatic blood flow, although the exact trigger mechanisms are not known yet, but could involve hypoperfusion and hypoxia. In the present paper all possible pathogenic paths to liver dysfunction in SIRS are reviewed.
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